p53 (DO-7) Antibody sc-47698 from Santa Cruz Biotechnology, Inc.

Product Specs
Itemp53 (DO-7) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-47698
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P), FCM
Reactivityhuman
Conjugate/TagUnconjugated
FormatPurified
Antibody TypePrimary Antibodies
CloneDO-7
Hostmouse
Targetp53
IsotypeIgG2b
NCBI Gene AliasesTRP53, BMFS5, P53, LFS1, BCC7
ClonalityMonoclonal
NCBI Full Gene Nametumor protein p53

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Noncanonical PI(4,5)P2 coordinates lysosome positioning through cholesterol traffickingSci AdvMay 22, 2026Ryan M. Loughran, Gurpreet K. Arora, Jiachen Sun, Alicia Llorente, Sophia Crabtree, Cynthia Y. Zhang, Kyanh Ly, Ren-Li Huynh, Wonhwa Cho, Brooke M. Emerlingcleaved caspase-3 (9664) were obtained from Cell Signaling Technology. Antibodies to p53 (human specific; sc-47698), LAMP-2 (Human specific; sc-18822), and HA (sc-7392) were acquired from Santa Cruz Biotechnologies.

(2) Stemness and Survival: CD117+/CD133+ Subpopulations Sustain PI3K Signaling and Drive Imatinib Resistance in Head and Neck Mucosal MelanomaCellsApril 19, 2026Sofie-Yasmin Hassan, Simeon Santourlidis, Thomas W. Flanagan, Sarah-Lilly Hassan, He Zhou, Morna F. Schmidt, Claudio Cacchi, Matthias Ferdinand Lammert, Mossad Megahed, Amir Sadegh Yazdi, et al.1:500; all from Cell Signaling Technology Inc., Danvers, MA, USA; anti-Actin 1:5.000 antibody, anti-p53 (SC-47698), 1:1000; MDM2 (SC-965), 1:1000, all from Santa Cruz Biotechnology Inc., Santa Cruz, CA, USA. Anti-PDK1

(3) Identification of senescence-associated drivers of tumour growth and progression using a novel microarray platformbioRxivDecember 26, 2025Hui-Ling Ou, Reuben Hoffmann, Rebecca Smith, Kaylyn Devlin, Mark Dane, Daniel Muñoz-Espín, James E KorkolaCell Signaling; S20, #9287, Cell Signaling); p53 (DO-1, #sc-126, Santa Cruz Biotechnologies; DO-7, #sc-47698, Santa Cruz Biotechnologies); p21 (#556431, BD Pharmingen) and GAPDH (#10494–1-AP, Proteintech). Peroxidase-conjugated

(4) Mitomycin C Induces Autophagy in Human Tracheal Fibroblasts and Suppresses Their GrowthLaryngoscope Investig OtolaryngolOctober 16, 2025Jeong-Mi Kim, Sungryeal Kim, Eun-Jeong Jeon, Jin-Mi Park, Seo-Young Park, Jeong-Seok Choisc376404), autophagy related gene 5 (ATG5, sc133158), Ras‐related protein 7 (Rab7, sc376362), p53 (sc47698), cyclin D1 (sc8369), glyceraldehyde 3‐phosphate dehydrogenase (GAPDH, sc17790) (all from Santa Cruz Biotechnology

(5) PPDPF is not a key regulator of human pancreas developmentPLoS GenetApril 7, 2025Markus Breunig, Meike Hohwieler, Jasmin Haderspeck, Felix von Zweydorf, Natalie Hauff, Lino-Pascal Pasquini, Christoph Wiegreffe, Eleni Zimmer, Medhanie A. Mulaw, Cécile Julier, et al.rabbit, 1:200, steamer citrate), GCG (Sigma, G2654, mouse, 1:1000, steamer citrate), P53 (Santa Cruz, sc-47698, mouse, 1:100, steamer citrate), P21 (Abcam, ab109520, rabbit, 1:300, steamer citrate), Ki-67 (DAKO,

(6) An organoid library of human esophageal squamous cell carcinomas (ESCCs) uncovers the chemotherapy-resistant ESCC featuresCommun BiolApril 1, 2025Shunsaku Nakagawa, Taku Sato, Eriko Ohashi, Mihoko Kajita, Fuyuki Miya, Kouhei Yamamoto, Hiroki Yotsumata, Kazuya Yamaguchi, Yasuaki Nakajima, Akinori Miura, et al.using a standard protocol. For immunohistochemistry, sections were incubated with anti-p53 antibody (sc47698, 1:100; Santa Cruz Biotechnology) overnight at 4 °C. The sections were then incubated with anti-mouse

(7) p53-regulated SESN1 and SESN2 regulate cell proliferation and cell death through control of STAT3Cell Commun SignalFebruary 22, 2025Alexander Haidurov, Andrei O. Zheltukhin, Anastasiya V. Snezhkina, George S. Krasnov, Anna V. Kudryavtseva, Andrei V. Budanov(Tyr1068) (D7A5), rabbit EGFR (D38B1) #4267 were from Cell Signaling Technology. Mouse p53 (DO-7) (sc-47698), GFP (C-2) (sc-390394) and β-Actin (C4) (sc-47778) were from Santa Cruz Biotechnology. Rabbit SESN2

(8) The ribotoxic stress response drives UV-mediated cell deathCellJuly 11, 2024Niladri K. Sinha, Connor McKenney, Zhong Y. Yeow, Jeffrey J. Li, Ki Hong Nam, Tomer M. Yaron-Barir, Jared L. Johnson, Emily M. Huntsman, Lewis C. Cantley, Alban Ordureau, et al.RRID:AB_330949 Phospho-p53 (Ser-15),Cell Signaling Technology,9284; RRID:AB_331464 p53 (DO-7),Santa Cruz Biotechnologies,sc-47698; RRID:AB_628083 ANTI-FLAG®,Millipore Sigma,A8592; RRID:AB_439702 ,, Bacterial and virus strains,Bacterial

(9) MRE11 and TREX1 control senescence by coordinating replication stress and interferon signalingNature communicationsJune 26, 2024Técher H, Gopaul D, Heuzé J, Bouzalmad N, Leray B, Vernet A, Mettling C, Moreaux J, Pasero P, Lin YL.Novus, NBS100-142), anti-cGAS (1/500, Cell Signaling, #15102), anti-p53 (1/500, Santa Cruz, clone DO7 sc-47698). Following antibodies were purchased from Abcam: anti-ATM (1:500, ab183324), anti-phospho S1981 ATM

(10) Combination of Etoposide and quercetin-loaded solid lipid nanoparticles Potentiates apoptotic effects on MDA-MB-231 breast cancer cellsHeliyonJune 15, 2024Reza Afarin, Fatemeh Ahmadpour, Mahdi Hatami, Sajad Monjezi, Somayeh Igdera 5 % non-fat milk solution. The membranes were treated with primary antibody against p53 (1: 1000; sc-47698), p21 (1: 1000; sc-271610) and GAPDH (1: 1000; sc-32233), proteins (Santa Cruz Biotechnology Inc., USA).

(11) Influence of Aldehyde Dehydrogenase Inhibition on Stemness of Endometrial Cancer Stem CellsCancers (Basel)May 27, 2024Beatriz Serambeque, Catarina Mestre, Gabriela Correia-Barros, Ricardo Teixo, Carlos Miguel Marto, Ana Cristina Gonçalves, Francisco Caramelo, Isabel Silva, Artur Paiva, Hans C. Beck, et al.mice (Santa Cruz Biotechnology, Inc., SC166362, USA), anti-P53 DO7 (Santa Cruz Biotechnology, Inc., SC47698, USA), and anti-Actin (Sigma-Aldrich, Israel). An appropriate anti-mouse secondary antibody (GE Healthcare,

(12) Helicobacter pylori Eradication Reverses DNA Damage Response Pathway but Not Senescence in Human Gastric EpitheliumInternational Journal of Molecular SciencesMarch 31, 2024Polyxeni Kalisperati, Evangelia Spanou, Ioannis S. Pateras, Konstantinos Evangelou, Irene Thymara, Penelope Korkolopoulou, Athanassios Kotsinas, Panayiotis G. Vlachoyiannopoulos, Athanasios G. Tzioufas, Christos Kanellopoulos, et al.clone JBW301, 06-636, Millipore, Merck, MA, USA) (mouse monoclonal), 1:1000], anti-p53 [(clone DO7, sc47698, Santa Cruz, TX, USA), (mouse monoclonal), 1:100], anti-phospho ATM [(Ser 1981, 10H11.E12, Merck, MA,

(13) Impact of intratumoral microbiome on tumor immunity and prognosis in human pancreatic ductal adenocarcinomaJournal of GastroenterologyMarch 1, 2024Shohei Abe, Atsuhiro Masuda, Tomonori Matsumoto, Jun Inoue, Hirochika Toyama, Arata Sakai, Takashi Kobayashi, Takeshi Tanaka, Masahiro Tsujimae, Kohei Yamakawa, et al.following antibodies were used: anti-TP53 (Santa Cruz Biotechnology, Dallas, TX, USA, catalog number: sc-47698), anti-CDKN2A/p16 (Roche Diagnostics, Cat #6695221001), anti-SMAD4 (Santa Cruz Biotechnology, Cat #sc-7966),

(14) Evaluation of the anti-cancer efficacy of lipid nanoparticles containing siRNA against HPV16 E6/E7 combined with cisplatin in a xenograft model of cervical cancerPLOS ONEFebruary 16, 2024Sung Wan Kang, Ok-Ju Kang, Ji-young Lee, Hyejeong Kim, Hunsoon Jung, Hongjoong Kim, Shin-Wha Lee, Yong Man Kim, Eun Kyung Choiat 4°C with the respective primary antibodies against HPV16 E7 (sc-6981, Santa Cruz, TX, USA), p53 (sc-47698, Santa Cruz, TX, USA), p21 (sc-817, Santa Cruz, TX, USA), PD-L1 (13684, Cell Signaling Technology, MA,

(15) CRISPR/Cas9 mediated Y-chromosome elimination affects human cells transcriptomeCell & BioscienceJanuary 30, 2024Ludovica Celli, Patrizia Gasparini, Ginevra Biino, Laura Zannini, Miriana Cardano(Sigma-Aldrich Cat# SAB1405848, RRID:AB_10739020; diluted 1:1000), p53-DO7 (Santa Cruz Biotechnology Cat# sc-47698, RRID:AB_628083; 1:500), cleaved PARP (Cell Signaling Technology Cat# 5625, RRID:AB_10699459; 1:1000),

(16) P53‑microRNA interactions regulate the response of colorectal tumor cells to oxaliplatin under normoxic and hypoxic conditionsOncology ReportsOctober 31, 2023Jiayu Zhang, Chenguang Li, Luanbiao Sun, Denghua Sun, Tiancheng Zhao4.6.2; Bio-Rad Laboratories, Inc.). The following antibodies were used: anti-p53 (1:1,000; cat. no. sc-47698; Santa Cruz Biotechnology, Inc.), anti-BCL-2 (1:1,000; cat. no. 15071), anti-MCL-1 (1:1,000; cat. no.

(17) AZD-7648, a DNA-PK Inhibitor, Induces DNA Damage, Apoptosis, and Cell Cycle Arrest in Chronic and Acute Myeloid Leukemia CellsInternational Journal of Molecular SciencesOctober 18, 2023Beatriz Santos Lapa, Maria Inês Costa, Diana Figueiredo, Joana Jorge, Raquel Alves, Ana Raquel Monteiro, Beatriz Serambeque, Mafalda Laranjo, Maria Filomena Botelho, Isabel Marques Carreira, et al.(Sigma-Aldrich, St. Louis, MO, USA, A5316) and anti-p53 DO7 (Santa Cruz Biotechnology, Inc., Dallas, TX, USA, sc-47698), was performed overnight at 4 °C with continuous agitation. Incubation with the secondary antibody

(18) A comprehensive analysis of tumor-stromal collagen in relation to pathological, molecular, and immune characteristics and patient survival in pancreatic ductal adenocarcinomaJournal of gastroenterologyOctober 1, 2023Ashina S, Masuda A, Yamakawa K, Hamada T, Tsujimae M, Tanaka T, Toyama H, Sofue K, Shiomi H, Sakai A, et al.and primary antibodies specific for TP53 (Santa Cruz Biotechnology, Dallas, TX, USA, catalog number: sc-47698), CDKN2A/p16 (Roche Diagnostics, catalog number: 705–4713), SMAD4 (Santa Cruz Biotechnology, catalog

(19) MLF2 Negatively Regulates P53 and Promotes Colorectal CarcinogenesisAdvanced science (Weinheim, Baden-Wurttemberg, Germany)September 1, 2023Fang D, Hu H, Zhao K, Xu A, Yu C, Zhu Y, Yu N, Yao B, Tang S, Wu X, et al.1:1000), p53 for immunofluorescence (Santa Cruz, sc‐126, 1:50), p53 for immunohistochemistry (Santa Cruz, sc‐47698, 1:50), Mdm2 (Santa Cruz, sc‐965, 1:500), p21 (Sigma, P1484, 1:5000), ubiquitin (Cell Signaling, #3936,

(20) The stress sensor GCN2 differentially controls ribosome biogenesis in colon cancer according to the nutritional contextMolecular oncologyJuly 15, 2023Piecyk M, Triki M, Laval PA, Duret C, Fauvre J, Cussonneau L, Machon C, Guitton J, Rama N, Gibert B, et al.

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p53 (DO-7) Antibody

p53 (DO-7) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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p53 (DO-7) Antibody from Santa Cruz Biotechnology, Inc.

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