Fig 2: Negative correlation of thyroid hormone receptor and STMN1 expression levels in clinical HCCs.(A) Immunohistochemical staining of THR and STMN1 in normal livers (N = 115) and HCCs (N = 115). Staining score were compared and plotted in (B). (C,D) Correlations of THRs and STMN1 expression levels were analyzed and indicated. (THRA vs. STMN1, Spearman r = -0.1723; 95% CI, -0.2986 to -0.04003; p = 0.0088. THRB vs. STMN1, Spearman r = 0.09029; 95% CI, -0.04341 to 0.2208; p = 0.1724). (E–J) THRA, THRB and STMN1 mRNA expression levels in three public liver cancer datasets from Oncomine were analyzed. (E,F Mas Liver, N = 115; G,H Roessler liver 2, N = 488; I,J Wurmbach liver, N = 75, respectively) (***P < 0.001; **P < 0.01, *P < 0.05). Error bars, s.e.m.