TRβ1 (J51) Antibody sc-737 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemTRβ1 (J51) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-737
NCBI Gene AliasesTHRbeta1, Thrbeta2, C-ERBA-2, GRTH, T3Rbeta, Nr1a2, c-erbAbeta, TRb, THRB1, ERBA2, TRbeta, Thrb2, C-ERBA-BETA, THRbeta, TRbeta1, NR1A2, THRB2, Thrb1, PRTH, T3R[b], THR1
Antibody TypePrimary Antibodies
ApplicationsWB, IP, IF, IHC(P)
Quantity200 µg/ml
CloneJ51
Reactivitymouse, rat, human
Hostmouse
Conjugate/TagUnconjugated
FormatPurified
ClonalityMonoclonal
NCBI Full Gene Namethyroid hormone receptor beta
TargetTRbeta1
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The Significance of Thyroid Hormone Receptors in Breast Cancer: A Hypothesis-Generating Narrative ReviewCurrent OncologyApril 23, 2024Trinity Quan, Jessica Cockburn, Sukhbinder Dhesy-Thind, Anita Bane, Hon Leong, Christopher Geleff, Catherine Devion, Noor Ajel, Katarzyna J. Jerzakexpressed in the cytoplasm of breast cancer cells (Table 2). An immunohistochemical analysis using the SC-737 antibody from Santa Cruz Biotechnology was done to determine the THRβ1 expression. Allred’s method was

(2) Hyperthyroidism exacerbates ischemic reperfusion injury in the kidneyEndocrine journalMarch 28, 2022Yamaguchi Y, Uchimura K, Takahashi K, Ishii T, Hanai S, Furuya F.

(3) Hypoxia-induced thyroid hormone receptor expression regulates cell-cycle progression in renal tubule epithelial cellsEndocrine journalNovember 29, 2021Hanai S, Uchimura K, Takahashi K, Ishii T, Mitsui T, Furuya F.

(4) ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1Biochemical and biophysical research communicationsOctober 22, 2021Wang W, Ledee D.10% normal donkey serum (NDS) for 1 hour. Cells were incubated overnight in 1.5% NDS with TRβ1, (# sc-737, Santa Cruz Biotechnology, Dallas, TX), ACAA2, or IgG isotype. The cells were washed with PBS and incubated

(5) Thyroid hormone receptor beta-1 expression in early breast cancer: a validation studyBreast cancer research and treatmentOctober 1, 2018Jerzak KJ, Cockburn JG, Dhesy-Thind SK, Pond GR, Pritchard KI, Nofech-Mozes S, Sun P, Narod SA, Bane A.

(6) Thyroid hormone suppresses expression of stathmin and associated tumor growth in hepatocellular carcinomaScientific reportsDecember 9, 2016Tseng YH, Huang YH, Lin TK, Wu SM, Chi HC, Tsai CY, Tsai MM, Lin YH, Chang WC, Chang YT, et al.(Calbiochem, 569391), rabbit polyclonal anti-THRA (GeneTex, GTX25621), mouse monoclonal anti-THRB (Santa Cruz, SC-737), mouse monoclonal anti-β-actin (Chemicon, MAB1501R), rabbit monoclonal anti-cyclin B1 (Abcam, ab32053),

(7) Hypothyroidism modifies morphometry and thyroid-hormone receptor expression in periurethral muscles of female rabbitsNeurourology and urodynamicsNovember 1, 2016Sánchez-García O, Rodríguez-Castelán J, Martínez-Gómez M, Cuevas E, Castelán F.

(8) Thyroid hormone receptor β1 suppresses proliferation and migration by inhibiting PI3K/Akt signaling in human colorectal cancer cellsOncology reportsSeptember 1, 2016Zhu L, Tian G, Yang Q, De G, Zhang Z, Wang Y, Nie H, Zhang Y, Yang X, Li J.

(9) Thyroid hormones upregulate apolipoprotein E gene expression in astrocytesBiochemical and biophysical research communicationsDecember 4, 2015Roman C, Fuior EV, Trusca VG, Kardassis D, Simionescu M, Gafencu AV.

(10) Ligand-dependent corepressor acts as a novel corepressor of thyroid hormone receptor and represses hepatic lipogenesis in miceJournal of hepatologyJanuary 1, 2012Song Y, Shan S, Zhang Y, Liu W, Ding W, Ren W, Xia H, Li X, Zhang Q, Zhao L, et al.

(11) Clinical relevance of thyroid dysfunction in human haematopoiesis: biochemical and molecular studiesEuropean journal of endocrinologyFebruary 1, 2010Kawa MP, Grymula K, Paczkowska E, Baskiewicz-Masiuk M, Dabkowska E, Koziolek M, Tarnowski M, Kłos P, Dziedziejko V, Kucia M, et al.secondary antibody. TRb-1 protein was detected using mouse monoclonal IgG-1 (clone: J51, reference: sc-737; Santa Cruz Biotech) with HRP-conjugated goat anti-mouse IgG-1 as the secondary antibody. The membranes

(12) Hypothyroidism enhances tumor invasiveness and metastasis developmentPloS oneJuly 29, 2009Martínez-Iglesias O, García-Silva S, Regadera J, Aranda A.standard protocols on deparaffinized sections as previously described [22]. The antibodies used were: TRβ (sc-737; Santa Cruz Biotechnology), cytokeratin 8/18 (NCL-5D3; Novocastra laboratories), vimentin (61013; Progen),

(13) A novel mutation (E333D) in the thyroid hormone beta receptor causing resistance to thyroid hormone syndromeExperimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes AssociationNovember 1, 2006Maraninchi M, Bourcigaux N, Dace A, El-Yazidi C, Malezet-Desmoulins C, Krempf M, Torresani J, Margotat A.

(14) Rapid nongenomic actions of thyroid hormoneProceedings of the National Academy of Sciences of the United States of AmericaSeptember 19, 2006Hiroi Y, Kim HH, Ying H, Furuya F, Huang Z, Simoncini T, Noma K, Ueki K, Nguyen NH, Scanlan TS, et al.

(15) Thyroid hormone receptor beta1 in normal colon and colorectal cancer-association with differentiation, polypoid growth type and K-ras mutationsInternational journal of cancerApril 1, 2006Hörkkö TT, Tuppurainen K, George SM, Jernvall P, Karttunen TJ, Mäkinen MJ.

(16) Thyroid hormone induces cardiac myocyte hypertrophy in a thyroid hormone receptor alpha1-specific manner that requires TAK1 and p38 mitogen-activated protein kinaseMolecular endocrinology (Baltimore, Md.)June 1, 2005Kinugawa K, Jeong MY, Bristow MR, Long CS.

(17) Parent-of-origin-specific binding of nuclear hormone receptor complexes in the H19-Igf2 imprinting control regionMolecular and cellular biologyJune 1, 2004Szabó PE, Pfeifer GP, Mann JR.

(18) Thyroid-hormone-dependent negative regulation of thyrotropin beta gene by thyroid hormone receptors: study with a new experimental system using CV1 cellsThe Biochemical journalMarch 1, 2004Nakano K, Matsushita A, Sasaki S, Misawa H, Nishiyama K, Kashiwabara Y, Nakamura H.

(19) Functional specificity of two hormone response elements present on the human apoA-II promoter that bind retinoid X receptor alpha/thyroid receptor beta heterodimers for retinoids and thyroids: synergistic interactions between thyroid receptor beta and upstream stimulatory factor 2aThe Biochemical journalDecember 1, 2003Hatzivassiliou E, Koukos G, Ribeiro A, Zannis V, Kardassis D.

(20) Synergism between nuclear receptors bound to specific hormone response elements of the hepatic control region-1 and the proximal apolipoprotein C-II promoter mediate apolipoprotein C-II gene regulation by bile acids and retinoidsThe Biochemical journalJune 1, 2003Kardassis D, Roussou A, Papakosta P, Boulias K, Talianidis I, Zannis VI.