Bioss Inc.'s TP/thymidine phosphorylase Antibody, PE-Cy5 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The TP/thymidine phosphorylase Antibody, PE-Cy5 Conjugated was generated using Thymidine Phosphorylase, and Tymp as the antigen and it reacts with Homo Sapiens, and Human.
Description
In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites