EPAS-1 (190b) Antibody sc-13596 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemEPAS-1 (190b) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-13596
Antibody TypePrimary Antibodies
NCBI Gene AliasesHRF, HIF2A, MOP2, bHLHe73, ECYT4, HLF, HIF-2alpha, PASD2
ApplicationsWB, IP, IF, IHC(P), ELISA
Clone190b
Quantity200 µg/ml
Reactivitymouse, rat, human
ClonalityMonoclonal
Hostmouse
FormatPurified
Conjugate/TagUnconjugated
NCBI Full Gene Nameendothelial PAS domain protein 1
IsotypeIgG1
TargetEPAS-1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Quantitative dissection of radioresistance in cancer cells: Oxygen depletion-induced biological versus chemical mechanisms and baseline mechanisms governed by HIF-1β-NRF2/TXNRD1NeoplasiaMay 15, 2026Satoshi Takeuchi, Minoru Kobayashi, Peter Wai Tik Lee, Itsuki Takahashi, Toshitada Yoshihara, Hiroshi Haradaanti-human HIF-1α (BD, Cat#610595), anti-mouse HIF-1α (Novus, Cat#NB100-479), anti-HIF-2α (Santa Cruz, Cat#sc-13596), anti-HIF-1β (Novus, Cat#NB100-124), or anti-CA9 (Novus, Cat#NB100-417) antibody as primary antibodies.

(2) Distinct HIF1α and HIF2α functions control skeletal muscle metabolism and erythropoiesisJournal of Clinical InvestigationApril 15, 2026Junhyeong Lee, Merc Emil Matienzo, Sangyi Lim, Edzel Evallo, Yeongsin Kim, Sujin Jang, Keon Kim, Chang Hyeon Choi, Youn Ho Han, Chang-Min Lee, et al.Cell Signaling Technology), GLUT4 (sc53566; Santa Cruz Biotechnology), HIF1α (NB-100-105; Novus Biologicals), HIF2α (sc13596; Santa Cruz Biotechnology), HSP90 (4874; Cell Signaling Technology), Lamin B1 (ab16048; Abcam), MYH2

(3) Distinct HIF1α and HIF2α functions control skeletal muscle metabolism and erythropoiesisJ Clin InvestFebruary 17, 2026Junhyeong Lee, Merc Emil Matienzo, Sangyi Lim, Edzel Evallo, Yeongsin Kim, Sujin Jang, Keon Kim, Chang Hyeon Choi, Youn Ho Han, Chang-Min Lee, et al.Cell Signaling Technology), GLUT4 (sc53566; Santa Cruz Biotechnology), HIF1α (NB-100-105; Novus Biologicals), HIF2α (sc13596; Santa Cruz Biotechnology), HSP90 (4874; Cell Signaling Technology), Lamin B1 (ab16048; Abcam), MYH2

(4) Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylationCardiovascular researchMarch 30, 2024Zhang J, Xu C, Tang X, Sun S, Liu S, Yang L, Chen Y, Yang Q, Wei TW, Wu X, et al.(Cell Signaling Technology, Danvers, MA, USA, cat. no. 4038S, 1:1000 dilution), HIF-2α (Santa Cruz Biotechnology, cat. No. sc-13596, 1:1000 dilution), endothelial NO synthase (eNOS) (Cell Signaling Technology, cat. no. 9572, 1:1000

(5) Critical role of VHL/BICD2/STAT1 axis in crystal-associated kidney diseaseCell death & diseaseOctober 13, 2023Hao W, Zhang H, Hong P, Zhang X, Zhao X, Ma L, Qiu X, Ping H, Lu D, Yin Y.anti-VHL (Abclonal, A0377) for Immunohistochemistry, anti- EPAS-1/HIF-2 alpha (Santa Cruz Biotechnology, sc-13596), anti-BICD2 (Abcam, ab237616), anti-GAPDH (TransGen Biotech, HC301-01), anti-β-Tubulin (ABclonal, AC021),

(6) Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer CellsJournal of medicinal chemistryJuly 27, 2023Zwergel C, Aventaggiato M, Garbo S, Di Bello E, Fassari B, Noce B, Castiello C, Lambona C, Barreca F, Rotili D, et al.this study: ACTB (Merck; A5316), HIF1-α (Cell Signaling; 14179), HIF2/EPAS-1 (Santa Cruz Biotechnology sc-13596), HXKII (Santa Cruz Biotechnology sc-6521), CAIX (Novus Biotechnology NB100-417), SIRT3 (Cell Signaling;

(7) ZnO Nanorods Create a Hypoxic State with Induction of HIF-1 and EPAS1, Autophagy, and Mitophagy in Cancer and Non-Cancer CellsInternational journal of molecular sciencesApril 9, 2023Aventaggiato M, Preziosi A, Cheraghi Bidsorkhi H, Schifano E, Vespa S, Mardente S, Zicari A, Uccelletti D, Mancini P, Lotti LV, et al.following primary antibodies were used: β-ACTIN (A5316), HIF-1α (Cell Signaling; 14179), HIF2/EPAS-1 (sc-13596, Santa Cruz Biotechnology, Dallas, TX, USA), HKII (sc-6521, Santa Cruz Biotechnology), CAIX (NB100-417,

(8) Transferrin Receptor-Mediated Iron Uptake Promotes Colon TumorigenesisAdvanced science (Weinheim, Baden-Wurttemberg, Germany)April 1, 2023Kim H, Villareal LB, Liu Z, Haneef M, Falcon DM, Martin DR, Lee HJ, Dame MK, Attili D, Chen Y, et al.Cell signaling Technology (Danvers, MA). Primary antibodies for TFRC (sc‐393719), HIF‐1α (sc‐13515), HIF‐2α (sc‐13596), pS6 (sc‐514033), pS6K (sc‐8418), p‐p53 (sc‐377567), p53 (sc‐6243), c‐MYC (sc‐40), GAPDH (sc‐47724),

(9) Transcriptomic alterations underlying metaplasia into specific metaplastic components in metaplastic breast carcinomaBreast cancer research : BCRJanuary 27, 2023Lien HC, Hsu CL, Lu YS, Chen TW, Chen IC, Li YC, Huang CS, Cheng AL, Lin CH.differentially expressed genes associated with lymph node metastasis. Primary antibodies against EPAS1 (SC13596; Santa Cruz Biotech, Dallas, TX, USA), SLC2A1 (SC377228), IL1RA (SC374084), CAV1 (EP353; Bio SB, Santa

(10) Macrophages regulate vascular smooth muscle cell function during atherosclerosis progression through IL-1β/STAT3 signalingCommunications biologyDecember 1, 2022Xue Y, Luo M, Hu X, Li X, Shen J, Zhu W, Huang L, Hu Y, Guo Y, Liu L, et al.antibodies against IL-1β (sc-12742, 1:2000), CD34 (sc-7324, 1:2000), VCAM-1 (sc-13160, 1:2000), and EPAS-1 (sc-13596, 1:2000) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Primary antibodies against

(11) Specific activation of hypoxia-inducible factor-2α by propionate metabolism via a β-oxidation-like pathway stimulates MUC2 production in intestinal goblet cellsBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieNovember 1, 2022Ma S, Yeom J, Lim YH.

(12) EP300 promotes renal tubular epithelial cell fibrosis by increasing HIF2α expression in diabetic nephropathyCellular signallingOctober 1, 2022Gong Y, Dou Y, Wang L, Wang X, Zhao Z.

(13) Characterization of rhodanine derivatives as potential disease-modifying drugs for experimental mouse osteoarthritisOsteoarthritis and cartilageSeptember 1, 2022Kwak JS, Lee Y, Yang J, Kim SK, Shin Y, Kim HJ, Choi JH, Im YJ, Kim MJ, Lee Yu K, et al.

(14) Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast CancerCancer DiscoveryMay 2, 2022Borja Ruiz-FernÃ¡ndez Ruiz-FernÃ¡ndez de CÃ³rdoba, Haritz Moreno, Karmele Valencia, Naiara Perurena, Pablo Ruedas, Thomas Walle, Alberto Pezonaga-Torres, Juan Hinojosa, Elisabet Guruceaga, Antonio Pineda-Lucena, et al.nitrocellulose membrane (Bio-Rad), and incubated with anti-Enpp1 (PA5-17097, Invitrogen), anti-Epas1 (sc-13596, Santa Cruz, RRID:AB_627525), anti-Srpx2 (Ab01584, Abcam), anti-Apcdd1 (sc-84694, Santa Cruz, RRID:AB_2057638),

(15) Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast CancerCancer discoveryMay 2, 2022Ruiz-Fernández de Córdoba B, Moreno H, Valencia K, Perurena N, Ruedas P, Walle T, Pezonaga-Torres A, Hinojosa J, Guruceaga E, Pineda-Lucena A, et al.nitrocellulose membrane (Bio-Rad), and incubated with anti-Enpp1 (PA5-17097, Invitrogen), anti-Epas1 (sc-13596, Santa Cruz, RRID:AB_627525), anti-Srpx2 (Ab01584, Abcam), anti-Apcdd1 (sc-84694, Santa Cruz, RRID:AB_2057638),

(16) Ocular Hypertension Results in Hypoxia within Glia and Neurons throughout the Visual ProjectionAntioxidants (Basel, Switzerland)April 29, 2022Jassim AH, Nsiah NY, Inman DM.mouse, Santa Cruz, Dallas, TX, USA, sc-13515), and HIF-2α (mouse, 1:1000, Santa Cruz, Dallas, TX, USA, sc-13596) was repeated at least three times with biological replicates [7,19]. 2.15. Statistical Analysis Statistical

(17) Hypoxia-induced HIF1α activation regulates small extracellular vesicle release in human embryonic kidney cellsScientific reportsJanuary 27, 2022Muñiz-García A, Romero M, Falcόn-Perez JM, Murray P, Zorzano A, Mora S.anti-HIF2α was from Bethyl, UK (cat. number: A700-003) used at 1:2,000 or Santa Cruz (cat. number: Sc-13596) used at 1:500; anti-β-tubulin was from Merck-Sigma Aldrich, (cat. number: T4026) and used at 1:2000;

(18) Mild chronic hypoxia-induced HIF-2α interacts with c-MYC through competition with HIF-1α to induce hepatocellular carcinoma cell proliferationCellular oncology (Dordrecht)October 1, 2021Mu H, Yu G, Li H, Wang M, Cui Y, Zhang T, Song T, Liu C.

(19) PBRM1 Cooperates with YTHDF2 to Control HIF-1α Protein TranslationCellsJune 8, 2021Shmakova A, Frost M, Batie M, Kenneth NS, Rocha S.primary antibodies were used for immunoblotting: HIF-1α (610958, BD Biosciences, Workingham, UK), HIF-2α (sc-13596, Santa Cruz, Dallas, TX, USA), HIF-1β (3718, Cell Signalling, Leiden, Holland), β-Actin (3700, Cell

(20) Physical confinement during cancer cell migration triggers therapeutic resistance and cancer stem cell-like behaviorCancer lettersMay 28, 2021Shen Q, Hill T, Cai X, Bui L, Barakat R, Hills E, Almugaiteeb T, Babu A, Mckernan PH, Zalles M, et al.

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EPAS-1 (190b) Antibody

EPAS-1 (190b) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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EPAS-1 (190b) Antibody from Santa Cruz Biotechnology, Inc.

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