Cdk8 (D-9) Antibody sc-13155 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCdk8 (D-9) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-13155
Antibody TypePrimary Antibodies
NCBI Gene AliasesK35, IDDHBA
CloneD-9
Reactivitymouse, rat, human
ApplicationsWB, IP, IF, IHC(P), ELISA
Quantity200 µg/ml
Conjugate/TagUnconjugated
Hostmouse
FormatPurified
ClonalityMonoclonal
NCBI Full Gene Namecyclin dependent kinase 8
TargetCdk8
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Discovery of a First-in-Class Murine Double Minute 2-Recruiting Positive Transcription Elongation Factor B PROTAC Degrader With Selective Antitumor ActivityMedComm (2020)April 9, 2026Xian Guan, Long Xie, Hanjun Guo, Lin Ma, Jiawei Zhou, Lisong Luo, Hao Yang, Yuanfang Wu, Jiangyu Liu, Yue Wang, et al.sc‐173), CDK6 (Cell Signaling Technology, 13331), CDK7 (Bethyl Laboratories, A300‐405A), CDK8 (Santa Cruz, sc‐13155), CDK11 (Abclonal, A12830), CDK12 (Cusabio, CSB‐PA882147LA01HU), CDK13 (Proteintech, 30461‐1‐AP), Cleaved

(2) Transcriptional regulation of protein synthesis by mediator kinase represents a therapeutic vulnerability in MYC-driven medulloblastomaNat CommunDecember 16, 2025Dong Wang, Caitlin Ritz, Yuhuan Luo, Ammu Suresh, Angela Pierce, Bethany Veo, Breauna Brunt, Nathan Dahl, Natalie Serkova, Sujatha Venkataraman, et al.were used: phospho-4EBP1 (Santa Cruz Biotechnology, sc-293124, 1:50), CDK8 (Santa Cruz Biotechnology, sc-13155, 1:50), CDK8 (Abcam, ab224828, 1:200), CDK8 (Invitrogen, PA5-11500, 1:200), fibrillarin (Abcam, EPR10823,

(3) Discovery of dCDK9-202 as a Highly Potent and Selective PROTAC CDK9 Degrader with Strong In Vivo Antitumor ActivityJ Med ChemOctober 23, 2025Lin Ma, Long Xie, Yue Wang, Xian Guan, Ying Zhang, Hanjun Guo, Jiawei Zhou, Jiyang Liu, Xingze Huang, Chunyu He, et al.sc-173), CDK6 (Cell Signaling Technology, 13331), CDK7 (Bethyl Laboratories, A300-405A), CDK8 (Santa Cruz, sc-13155), CDK11 (Abclonal, A12830), CDK12 (Cusabio, CSB-PA882147LA01HU), cleaved caspase-3 (Diagbio, db15982),

(4) The Cyclin-Dependent Kinase 8 Inhibitor E966-0530-45418 Attenuates Pulmonary Fibrosis In Vitro and In VivoInternational journal of biological sciencesJanuary 1, 2025Chou CH, Huang WJ, Hsu KC, Hsu JY, Lin TE, Yang CR.lysates were immunoprecipitated with 1 µg of mouse anti-CDK8 antibody (Santa Cruz, Dallas, Texas, USA, sc-13155, 1:20) and Protein A/G MagBeads (Genscript, Piscataway, NJ, USA, L00277) overnight at 4 °C. After the

(5) Transcriptional Regulation of Protein Synthesis by Mediator Kinase Represents a Therapeutic Vulnerability in MYC-driven MedulloblastomaResearch SquareNovember 1, 2024Rajeev Vibhakar, Caitlin Wang, Caitlin Pierce, Bethany Pierce, Bethany Veo, Breauna Brunt, Breauna Brunt, Nathan Suresh, Natalie Serkova, Natalie Venkataraman, et al.were used: phospho-4EBP1 (Santa Cruz Biotechnology, sc-293124, 1:50), CDK8 (Santa Cruz Biotechnology, sc-13155, 1:50), CDK8 (Abcam, ab224828, 1:200), CDK8 (Invitrogen, PA5–11500, 1:200), fibrillarin (Abcam, EPR10823,

(6) An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase IIMolecular CellJuly 25, 2024Haiyan Zhao, Jiaqin Li, Yufei Xiang, Sohail Malik, Supriya V. Vartak, Giovana M. B. Veronezi, Natalie Young, McKayla Riney, Jens Kalchschmidt, Andrea Conte, et al.monoclonal anti-Pol II 8WG16 (sc-56767), anti-RXRα(sc-46659), anti-MED25(sc-393759), and anti-Cdk8(sc-13155) antibodies were from Santa Cruz. Anti-MED13 (91684S) was from Cell Signaling Technology. Polyclonal

(7) PAX3-FOXO1 coordinates enhancer architecture, eRNA transcription, and RNA polymerase pause release at select gene targetsMolecular cellDecember 1, 2022Zhang S, Wang J, Liu Q, McDonald WH, Bomber ML, Layden HM, Ellis J, Borinstein SC, Hiebert SW, Stengel KR.

(8) Cyclin-dependent kinase 8 is an independent prognosticator in uterine leiomyosarcomaPathology, research and practiceJuly 1, 2022Yasutake N, Iwasaki T, Yamamoto H, Sonoda K, Kodama K, Okugawa K, Asanoma K, Yahata H, Kato K, Oda Y.

(9) LATS1 is a central signal transmitter for achieving full type-I interferon activityScience advancesApril 8, 2022Zuo Y, He J, Liu S, Xu Y, Liu J, Qiao C, Zang L, Sun W, Yuan Y, Zhang H, et al.1:1000), anti–Pan-pY (Cell Signaling Technology, 8954S; 1:1000), anti-CDK8 (Santa Cruz Biotechnology, sc-13155; 1:1000), anti-p65 (Cell Signaling Technology, 8242S; 1:1000), anti-p-p65 (Cell Signaling Technology,

(10) MED13L integrates Mediator-regulated epigenetic control into lung cancer radiosensitivityTheranosticsJanuary 1, 2020Zhang N, Song Y, Xu Y, Liu J, Shen Y, Zhou L, Yu J, Yang M.dilution; Bethyl, A302-421A), MED12 (1:5000 dilution; Bethyl, A300-774A), CDK8 (1:250 dilution; Santa Cruz, sc-13155), CCNC (1:5000 dilution; Bethyl, A301-989A), MED8 (1:500 dilution; Santa Cruz, sc-365960), MED6 (1:500

(11) miR-152-3p Modulates hepatic carcinogenesis by targeting cyclin-dependent kinase 8Pathology, research and practiceJune 1, 2019Yin T, Liu MM, Jin RT, Kong J, Wang SH, Sun WB.

(12) Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activityBioorganic chemistryDecember 1, 2018Bian J, Ren J, Li Y, Wang J, Xu X, Feng Y, Tang H, Wang Y, Li Z.

(13) The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic ReprogrammingCell metabolismMay 1, 2018Tang HW, Hu Y, Chen CL, Xia B, Zirin J, Yuan M, Asara JM, Rabinow L, Perrimon N.(Cell Signaling, 9624), anti-Flag (Sigma, F3165), anti-HA (Covance/BioLegend, MMS-101P), anti-CDK8 (Santa Cruz, sc-13155 ), anti-LC3B (Cell Signaling, 2775), anti-human CPSF6 (Santa Cruz, sc-100692), anti-ubiquitin FK2 (Enzo life Science

(14) Cyclin-dependent kinase 9 links RNA polymerase II transcription to processing of ribosomal RNAThe Journal of biological chemistryJuly 19, 2013Burger K, Mühl B, Rohrmoser M, Coordes B, Heidemann M, Kellner M, Gruber-Eber A, Heissmeyer V, Strässer K, Eick D.

(15) Tumor-suppressive effects of CDK8 in endometrial cancer cellsCell cycle (Georgetown, Tex.)March 15, 2013Gu W, Wang C, Li W, Hsu FN, Tian L, Zhou J, Yuan C, Xie XJ, Jiang T, Addya S, et al.

(16) Adenovirus L-E1A activates transcription through mediator complex-dependent recruitment of the super elongation complexJournal of virologyMarch 1, 2013Vijayalingam S, Chinnadurai G.

(17) The histone variant macroH2A suppresses melanoma progression through regulation of CDK8NatureDecember 23, 2010Kapoor A, Goldberg MS, Cumberland LK, Ratnakumar K, Segura MF, Emanuel PO, Menendez S, Vardabasso C, Leroy G, Vidal CI, et al.quality control. For CDK8 staining, mH2A negative melanomas were stained (Santa Cruz sc-1521; 1:200 and sc-13155; 1:15), followed by randomization and scoring. All statistical analyses were conducted using SPSS 14

(18) Roscovitine inhibits thyroid hormone-induced tail regression of the frog tadpole and reveals a role for cyclin C/Cdk8 in the establishment of the metamorphic gene expression programDevelopmental dynamics : an official publication of the American Association of AnatomistsDecember 1, 2008Skirrow RC, Veldhoen N, Domanski D, Helbing CC.

(19) Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardationMolecular cellAugust 8, 2008Ding N, Zhou H, Esteve PO, Chin HG, Kim S, Xu X, Joseph SM, Friez MJ, Schwartz CE, Pradhan S, et al.

(20) MED1 phosphorylation promotes its association with mediator: implications for nuclear receptor signalingMolecular and cellular biologyJune 1, 2008Belakavadi M, Pandey PK, Vijayvargia R, Fondell JD.