Bax (B-9) Antibody from Santa Cruz Biotechnology, Inc.

The Bax (B-9) antibody has been shown to work effectively in various applications, including Western blotting, flow cytometry, immunofluorescence, immunohistochemistry on paraffin-embedded sections, and immunoprecipitation.

Yes, the Bax antibody is reactive with human cells and has been cited in numerous studies, including those involving human cancer cell lines such as HeLa and A2780, where it has been utilized to investigate apoptosis and cell survival mechanisms.

Yes, the Bax antibody has been utilized in research to explore apoptosis mechanisms, such as in studies that examine the role of Bax in caspase activation and the regulation of cell death pathways in response to various treatments, including chemotherapeutic agents.

The Bax antibody has been employed in studies investigating drug resistance mechanisms in cancer, such as its role in modulating apoptosis in response to treatments like cisplatin. Research has shown that alterations in Bax expression can influence the sensitivity of cancer cells to chemotherapy, making it a valuable tool for understanding resistance pathways.