Cdk9 (D-7) Antibody sc-13130 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCdk9 (D-7) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-13130
NCBI Gene AliasesCDC2L4, CTK1, PITALRE, C-2k, TAK
Antibody TypePrimary Antibodies
Quantity200 µg/ml
Reactivitymouse, rat, human
ApplicationsWB, IP, IF, IHC(P), ELISA
CloneD-7
Hostmouse
Conjugate/TagUnconjugated
FormatPurified
ClonalityMonoclonal
NCBI Full Gene Namecyclin dependent kinase 9, cyclin dependent kinase 9 (CDC2-related kinase)
TargetCdk9
IsotypeIgG2b

Questions and Answers

What applications has the CDK9 (D-7) antibody been used for in scientific research?

The CDK9 (D-7) antibody has been shown to work in various applications, including Western blotting, ELISA, immunofluorescence, immunohistochemistry, and immunoprecipitation, as evidenced by its use in multiple studies.

Can this antibody be used to study CDK9 in different species?

Yes, the CDK9 (D-7) antibody is reactive with mouse, human, and rat samples, making it suitable for studies involving these species.

Are there any specific studies that highlight the role of CDK9 in cancer research?

Yes, one study demonstrated that the multiple CDK inhibitor dinaciclib, which targets CDK9, effectively suppressed neuroblastoma growth by inhibiting CDK2 and CDK9 activity, suggesting that CDK9 is a potential therapeutic target in cancer treatment ().

Has the CDK9 antibody been utilized in any studies related to viral infections?

Yes, the CDK9 (D-7) antibody was used in research that identified its role in enhancing HIV transcription by promoting RNA polymerase II activity, indicating its importance in the context of viral gene expression ().

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Discovery of a First-in-Class Murine Double Minute 2-Recruiting Positive Transcription Elongation Factor B PROTAC Degrader With Selective Antitumor ActivityMedComm (2020)April 9, 2026Xian Guan, Long Xie, Hanjun Guo, Lin Ma, Jiawei Zhou, Lisong Luo, Hao Yang, Yuanfang Wu, Jiangyu Liu, Yue Wang, et al.The following primary antibodies were used: CDK9 (Cell Signaling Technology, 2316), CDK9 (Santa Cruz, sc‐13130), Cyclin T1 (Cell Signaling Technology, 81464), Cyclin T2 (Santa Cruz, sc‐81243), p53 (Santa Cruz, sc‐126),

(2) Discovery of dCDK9-202 as a Highly Potent and Selective PROTAC CDK9 Degrader with Strong In Vivo Antitumor ActivityJ Med ChemOctober 23, 2025Lin Ma, Long Xie, Yue Wang, Xian Guan, Ying Zhang, Hanjun Guo, Jiawei Zhou, Jiyang Liu, Xingze Huang, Chunyu He, et al.Various primary antibodies were used to detect CDK9 (Cell Signaling Technology, 2316), CDK9 (Santa Cruz, sc-13130), ACTIN (Proteintech, 66009-1-Ig), GAPDH (Cell Signaling Technology, 2118), CDK1/2 (Santa Cruz, sc-53219),

(3) Activation of the stress-activated protein kinase JNK in response to herpes simplex virus-1 infection coordinates transition of BRD4 from chromosome association to transcription elongationThe Journal of biological chemistrySeptember 1, 2025Sun W, Ren K, Li J, Zhang M, Jiang Q, Wang L, Li E.MAPK, Rpb-1 CTD (#2629) were purchased from Cell Signaling Technology. Antibodies to CDK9 (Santa Cruz, sc-13130), to BRD4 (Abcam, ab128874), to Lamin B1 (Beyotime, AF5222), to ICP0 (HSV-1 and -2, Santa Cruz, sc-53070),

(4) Identification of a TNIK-CDK9 Axis as a Targetable Strategy for Platinum-Resistant Ovarian CancerMolecular Cancer TherapeuticsApril 2, 2025Noah Puleo, Harini Ram, Michele L. Dziubinski, Dylan Carvette, Jessica Teitel, Sreeja C. Sekhar, Karan Bedi, Aaron Robida, Michael M. Nakashima, Sadaf Farsinejad, et al.anti-RNA polymerase II CTD repeat YSPTSPS (phospho S2; ab5095, RRID:AB_304749); (iii) Santa Cruz Biotechnology: CDK9 (sc-13130, RRID:AB_627245); and (iv) Thermo Fisher Scientific: TCF4 (22337-1-AP, RRID:AB_2879076). RNA extraction

(5) Liquid–liquid phase separation of LARP7 restrains HIV-1 replicationEMBO ReportsMarch 20, 2025Zhuoxin Li, Xiya Fang, Bing Zhao, Ran Liu, Yezhuang Shen, Tingting Li, Yining Wang, Zenglin Guo, Wen Wang, Biyu Zhang, et al.T1,Santa Cruz,Cat# sc-271348 Mouse anti-Flag,Sigma-Aldrich,Cat# F3165 Rabbit anti-CDK9,Santa Cruz,Cat# sc-13130 Goat anti-MEPCE,Novus,Cat# NB100-93420 Mouse anti-NPM1,Abcam,Cat# ab10530 Goat anti-HEXIM1,Abcam,Cat#

(6) Targeting N-Myc in neuroblastoma with selective Aurora kinase A degradersCell chemical biologyFebruary 20, 2025Tang J, Moorthy R, Hirsch LE, Demir Ö, Baker ZD, Naumann JA, Jones KFM, Grillo MJ, Haefner ES, Shi K, et al.(DCS83) 1:500,Cell signaling technology,Cat# 3136 CDK9 (D-7) 1:2000,Santa Cruz Biotechnology,Cat# sc-13130 Cyclin D1 (92G2) 1:500,Cell signaling technology,Cat# 2978 Cyclin D2 (D52F9) 1:500,Cell signaling technology

(7) TurboCas: A method for locus-specific labeling of genomic regions and isolating their associated protein interactomeMolecular CellDecember 19, 2024Bercin K. Cenik, Yuki Aoi, Marta Iwanaszko, Benjamin C. Howard, Marc A. Morgan, Grant D. Andersen, Elizabeth T. Bartom, Ali Shilatifard,Cell Signaling Technologies,"CAT #13440, RRID# AB_2687578" Cdk9 Antibody (D-7),Santa Cruz Biotechnology,Cat# sc-13130 Auxin inducible degron antibody,"Zheng et al., 2021",N/A c-Fos (9F6) Rabbit mAb,Cell Signaling Technology,"Cat#

(8) Evolutionary analysis reveals the role of a non-catalytic domain of peptidyl arginine deiminase 2 in transcriptional regulationiScienceApril 19, 2024José Luis Villanueva-Cañas, Narcis Fernandez-Fuentes, Dominik Saul, Robyn Laura Kosinsky, Catherine Teyssier, Malgorzata Ewa Rogalska, Ferran Pegenaute Pérez, Baldomero Oliva, Cedric Notredame, Miguel Beato, et al.visualized by 4% to 12% SDS-PAGE gels and western blotting, using anti-GFP (11814460001, Roche), anti-CDK9 (sc-13130, Santa Cruz), or anti-CCNT1 (A303-499A, Bethyl Labs) were used for western blots. Multiple sequence alignments

(9) ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genesNat CommunDecember 14, 2023Heeyoun Bunch, Deukyeong Kim, Masahiro Naganuma, Reiko Nakagawa, Anh Cong, Jaehyeon Jeong, Haruhiko Ehara, Hongha Vu, Jeong Ho Chang, Matthew J. Schellenberg, et al.were Pol II (ab817, Abcam; #2629, Cell Signaling Technology; A304-405A, Bethyl Laboratories), CDK9 (sc-13130, Santa Cruz Biotechnology), MED23 (A300-425A, Bethyl Laboratories), ELK1 (sc-365876, Santa Cruz Biotechnology;

(10) Exploiting a rodent cell block for intrinsic resistance to HIV-1 gene expression in human T cellsmBioOctober 31, 2023Ryan T. Behrens, Jyothi Krishnaswamy Rajashekar, James W. Bruce, Edward L. Evans, Amelia M. Hansen, Natalia Salazar-Quiroz, Lacy M. Simons, Paul Ahlquist, Judd F. Hultquist, Priti Kumar, et al.elution were separated by SDS-PAGE and immunoblotted with mouse anti-CDK9 (Santa Cruz Biosciences, sc-13130) and mouse anti-CCNT1 (Santa Cruz Biosciences, sc-271348) as described above. Transcriptome analysis For

(11) Identification of a diketopiperazine-based O-GlcNAc transferase inhibitor sensitizing hepatocellular carcinoma to CDK9 inhibitionThe FEBS journalSeptember 1, 2023Shan X, Jiang R, Gou D, Xiang J, Zhou P, Xia J, Wang K, Huang A, Tang N, Huang L.

(12) Piperlongumine conjugates induce targeted protein degradationCell chemical biologyFebruary 16, 2023Pei J, Xiao Y, Liu X, Hu W, Sobh A, Yuan Y, Zhou S, Hua N, Mackintosh SG, Zhang X, et al.

(13) PGC-1α senses the CBC of pre-mRNA to dictate the fate of promoter-proximally paused RNAPIIMolecular cellJanuary 19, 2023Rambout X, Cho H, Blanc R, Lyu Q, Miano JM, Chakkalakal JV, Nelson GM, Yalamanchili HK, Adelman K, Maquat LE.

(14) Modulation of FLT3-ITD and CDK9 in acute myeloid leukaemia cells by novel proteolysis targeting chimera (PROTAC)European journal of medicinal chemistryDecember 5, 2022Řezníčková E, Krajčovičová S, Peřina M, Kovalová M, Soural M, Kryštof V.

(15) ERK-mediated NELF-A phosphorylation promotes transcription elongation of immediate-early genes by releasing promoter-proximal pausing of RNA polymerase IINature communicationsDecember 3, 2022Ohe S, Kubota Y, Yamaguchi K, Takagi Y, Nashimoto J, Kozuka-Hata H, Oyama M, Furukawa Y, Takekawa M.

(16) DDB1 prepares brown adipocytes for cold-induced thermogenesisLife MetabolismNovember 3, 2022Xu Wang, Shen-Ying Liu, Guo-Sheng Hu, Hao-Yan Wang, Guo-Liang Zhang, Xiang Cen, Si-Ting Xiang, Wen Liu, Peng Li, Haobin Ye, et al.(1:1000, Proteintech, 66369-1-Ig), anti-CyclinT1 (1:1000, CST, 81464), anti-CDK9 (1:1000, Santa Cruz, sc-13130), anti-RNA Polymerase II (1:1000, Bethyl, A300-653A), anti-GAPDH (1:5000, Proteintech, 60004-1), and

(17) Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancerMolecular cellNovember 3, 2022Song L, Yao X, Li H, Peng B, Boka AP, Liu Y, Chen G, Liu Z, Mathias KM, Xia L, et al.(Novus Biologicals, NB600–501) diluted 1:2000, AFF4 (Santa Cruz, sc-390130) diluted 1:1000, CDK9 (Santa Cruz, sc-13130) diluted 1:1000, ELL2 (Santa Cruz, sc-376611), and DOT1L (Cell Signaling Technology, 77087s) diluted

(18) Identification of Novel Nucleocapsid Chimeric Proteins Inhibiting HIV-1 ReplicationInternational journal of molecular sciencesOctober 15, 2022Kim HI, Kim GN, Yu KL, Park SH, You JC.anti-GFP (Cat. #sc-9996), anti-GAPDH (Cat. #sc-47724), anti-CycT1 (Cat. #sc-271348), and anti-CDK9 (Cat. #sc-13130) antibodies were obtained from Santa Cruz Biotechnology. Anti-FLAG (Cat. #F3165) antibody was purchased

(19) Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complexCell reportsApril 12, 2022Ohno SI, Oikawa K, Tsurui T, Harada Y, Ono K, Tateishi M, Mirza A, Takanashi M, Kanekura K, Nagase K, et al.

(20) cAMP-Induced Nuclear Condensation of CRTC2 Promotes Transcription Elongation and Cystogenesis in Autosomal Dominant Polycystic Kidney DiseaseAdvanced science (Weinheim, Baden-Wurttemberg, Germany)April 1, 2022Mi Z, Song Y, Wang J, Liu Z, Cao X, Dang L, Lu Y, Sun Y, Xiong H, Zhang L, et al.excited with a 488 nm laser for 5 min. Then incubated with primary antibody against CDK9 (Santa Cruz, sc‐13130) or CycT1 (Santa Cruz, sc‐8127). The samples were imaged by ZEISS LSM900 confocal microscope with a

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Cdk9 (D-7) Antibody

Cdk9 (D-7) Antibody from Santa Cruz Biotechnology, Inc.

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Questions and Answers

Santa Cruz Biotechnology, Inc.

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Cdk9 (D-7) Antibody from Santa Cruz Biotechnology, Inc.

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