α-Adaptin 1/2 (C-8) Antibody sc-17771 from Santa Cruz Biotechnology, Inc.

Product Specs
Itemα-Adaptin 1/2 (C-8) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-17771
NCBI Gene AliasesADTAB, Adtaa, 2410074K14Rik, Adtab, ADTAA, HIP-9, AP2-ALPHA, HIP9, HYPJ, L25, CLAPA1, CLAPA2
Antibody TypePrimary Antibodies
Reactivitymouse, rat, human
Quantity200 µg/ml
CloneC-8
ApplicationsWB, IP, IF, IHC(P), ELISA
FormatPurified
Hostmouse
ClonalityMonoclonal
Conjugate/TagUnconjugated
NCBI Full Gene Nameadaptor-related protein complex 2, alpha 1 subunit, adaptor-related protein complex 2, alpha 2 subunit, adaptor related protein complex 2 subunit alpha 2, adaptor related protein complex 2 subunit alpha 1
Targetalpha-Adaptin 2
IsotypeIgG2a

Add to Compare List

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) CCDC32 stabilizes clathrin-coated pits and drives their invaginationElifeJanuary 5, 2026Ziyan Yang, Changsong Yang, Zheng Huang, Peiliu Xu, Yueping Li, Lu Han, Linyuan Peng, Xiangying Wei, John E Pak, Tatyana Svitkina, et al.for mass spectrometry analysis. Anti-α-Adaptin 1/2 Antibody (C-8) (Santa Cruz Biotechnology, Catalog #sc-17771) was used in WB to detect AP2 enrichments. Mass spectrometry analysis Samples were digested overnight

(2) CCDC32 stabilizes clathrin-coated pits and drives their invaginationElifeJanuary 5, 2026Ziyan Yang, Changsong Yang, Zheng Huang, Peiliu Xu, Yueping Li, Lu Han, Linyuan Peng, Xiangying Wei, John E Pak, Tatyana Svitkina, et al.for mass spectrometry analysis. Anti-α-Adaptin 1/2 Antibody (C-8) (Santa Cruz Biotechnology, Catalog #sc-17771) was used in WB to detect AP2 enrichments. Mass spectrometry analysis Samples were digested overnight

(3) Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanismScience AdvancesSeptember 12, 2025Jingyi Wu, Chun Wan, Yuan Tian, Yan Ouyang, Harrison Puscher, Suzhao Li, Qian Yin, Jingshi ShenThe endogenous AP2 α subunit was labeled using anti–α-adaptin antibodies (Santa Cruz Biotechnology, #sc-17771, RRID: AB_2274034) and Alexa Fluor 568–conjugated secondary antibodies (Thermo Fisher Scientific, #A11004,

(4) The scaffold protein IQGAP1 promotes reorientation of epithelial cell polarity at the two‐cell stage for cystogenesisGenes to CellsDecember 1, 2024Michihiro Horikawa, Junya Hayase, Sachiko Kamakura, Akira Kohda, Masafumi Nakamura, Hideki Sumimotoanti‐IQGAP1 (H‐109; #sc‐10792) rabbit polyclonal antibodies and the anti‐AP2α mouse monoclonal antibody (C‐8; #sc‐17771) from Santa Cruz Biotechnology; the anti‐AP2β rabbit monoclonal antibody (EPR7567; #ab129168) from Abcam;

(5) An AAGAB-to-CCDC32 handover mechanism controls the assembly of the AP2 adaptor complexProceedings of the National Academy of SciencesAugust 20, 2024Chun Wan, Harrison Puscher, Yan Ouyang, Jingyi Wu, Yuan Tian, Suzhao Li, Qian Yin, Jingshi ShenAB_2633282). The endogenous AP2 α subunit was labeled using anti-α-adaptin (Santa Cruz Biotechnology, #sc-17771, RRID: AB_2274034) and Alexa Fluor 488–conjugated secondary antibodies. Endogenous β-COP was labeled

(6) ArfGAP1 inhibits mTORC1 lysosomal localization and activationThe EMBO journalJune 15, 2021Meng D, Yang Q, Melick CH, Park BC, Hsieh TS, Curukovic A, Jeong MH, Zhang J, James NG, Jewell JL.and β‐COP (#G2279, 1: 1,000) were obtained from Sigma. AP‐1 (#sc‐398867, 1:1,000), AP‐2 Adaptin 1/2 (#sc‐17771, 1:2,000), AP‐3 (#sc‐136277, 1:1,000), AP‐4 (#sc‐135835, 1:1,000), CHC (#sc‐12734, 1:1,000), HA (#sc‐7392,

(7) Clathrin regulates Wnt/β-catenin signaling by affecting Golgi to plasma membrane transport of transmembrane proteinsJournal of cell scienceJuly 9, 2020Munthe E, Raiborg C, Stenmark H, Wenzel EM.Chromotek; IF 1:500); mouse anti-AP-2µ2 (612620, BD Transduction Laboratories; WB 1:500); mouse anti-AP-2α (sc-17771, Santa Cruz Biotechnologies; WB 1:1000); rabbit anti-Pan-cadherin (ab6529, Abcam; IF 1:100, WB 1:1000);

(8) Renal functional effects of the highly selective AT2R agonist, β-Pro7 Ang III, in normotensive ratsClinical science (London, England : 1979)April 17, 2020Krause LMH, Kemp BA, Tan ASJ, Jones ES, Del Borgo MP, Aguilar MI, Denton KM, Carey RM, Widdop RE.incubated with the primary antibodies AT2 R (1:100) and adaptor protein-2 (AP-2; Santa Cruz; Cat # sc-17771; 1:100) in 1% milk TBST2 overnight at 4◦ C. After washing with 874 © 2020 The Author(s). This is an

(9) Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradationScientific reportsJanuary 20, 2020Jones S, King PJ, Antonescu CN, Sugiyama MG, Bhamra A, Surinova S, Angelopoulos N, Kragh M, Pedersen MW, Hartley JA, et al.Technology), rabbit Clathrin Heavy Chain (4796, D3C6 XP, Cell Signalling Technology), mouse α-Adaptin 1/2 (sc-17771, C-8, Santa Cruz Biotechnology), rabbit Caveolin-1 (3267, D46G3, Cell Signalling Technology), mouse

(10) AAGAB Controls AP2 Adaptor Assembly in Clathrin-Mediated EndocytosisDevelopmental cellAugust 19, 2019Gulbranson DR, Crisman L, Lee M, Ouyang Y, Menasche BL, Demmitt BA, Wan C, Nomura T, Ye Y, Yu H, et al.AP2 adaptor),BD Biosciences,"Cat# 610502, RRID:AB_397868" α-adaptin,Santa Cruz Biotechnology,"Cat# SC-17771, RRID:AB_2274034" α-tubulin,eBioscience,"Cat# 14-4502-82, RRID:AB_1210456" AAGAB,Bethyl,Cat# A305-593A β2

(11) Defective Renal Angiotensin III and AT₂ Receptor Signaling in Prehypertensive Spontaneously Hypertensive RatsJournal of the American Heart AssociationMay 7, 2019Kemp BA, Howell NL, Keller SR, Gildea JJ, Shao W, Navar LG, Carey RM.permeabilization with 0.2% Triton‐X detergent: (1) AT2R (1:100), adaptor protein 2 (AP‐2; Santa Cruz; Cat # sc‐17771; 1:100), and phalloidin (1:200). (2) NHE‐3 (Millipore; Cat # MAB3136; 1:2000) and AP‐2 (Santa Cruz;

(12) A nanobody-based molecular toolkit provides new mechanistic insight into clathrin-coat initiationeLifeApril 30, 2019Traub LM.Biotechnology,sc-47779,"1:10,000 for immunoblotting" Antibody,anti-AP-2 α subunit mouse mAb C-8,Santa Cruz Biotechnology,sc-17771,1:500 for immunoblotting Antibody,anti-AP-2 α subunit; mouse clone mAb AP.6,F Brodsky Laboratory,PMID:

(13) IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signalingeLifeApril 11, 2018Yoneyama Y, Lanzerstorfer P, Niwa H, Umehara T, Shibano T, Yokoyama S, Chida K, Weghuber J, Hakuno F, Takahashi SI.antibody (sc-8299), anti-clathrin HC antibody (sc-12734; for immunoblotting), anti-α-adaptin antibody (sc-17771), anti-γ-adaptin antibody (sc-10763), anti-p70 S6K antibody (sc-230), anti-HSP90 antibody (sc-7947),

(14) Lysosomal targeting of SIDT2 via multiple YxxΦ motifs is required for SIDT2 function in the process of RNautophagyJournal of cell scienceSeptember 1, 2017Contu VR, Hase K, Kozuka-Hata H, Oyama M, Fujiwara Y, Kabuta C, Takahashi M, Hakuno F, Takahashi SI, Wada K, et al.

(15) Multiple dynamin family members collaborate to drive mitochondrial divisionNatureDecember 1, 2016Lee JE, Westrate LM, Wu H, Page C, Voeltz GK.Santa Cruz Biotech), GAPDH (G9545, Sigma-Aldrich), and the monoclonal mouse antibody against AP-1/2 (sc-17771, Santa Cruz Biotech.), Drp1 (ab56788, Abcam), Dynamin (610245, BD Biosciences), cytochrome C (sc-13560,

(16) Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal systemThe Journal of cell biologyAugust 1, 2016McLelland GL, Lee SA, McBride HM, Fon EA.reagents Antibodies used in this study include antiactin (MAB1501; EMD Millipore), anti–α-adaptin (sc-17771; Santa Cruz Biotechnology, Inc.), anti-CD63 (556019; BD), anti-DNA (61014; Progen), anti-Drp1 (611113;

(17) ERK1-Based Pathway as a New Selective Mechanism To Modulate CCR5 with Natural AntibodiesJournal of immunology (Baltimore, Md. : 1950)October 1, 2015Venuti A, Pastori C, Siracusano G, Riva A, Sciortino MT, Lopalco L.

(18) Herpes simplex virus internalization into epithelial cells requires Na+/H+ exchangers and p21-activated kinases but neither clathrin- nor caveolin-mediated endocytosisJournal of virologyNovember 1, 2014Devadas D, Koithan T, Diestel R, Prank U, Sodeik B, Döhner K.infection. This suggests either that HSV-1 is inter- protein 4 (ICP4, 58S [45]), anti-adaptin 1/2 (sc-17771; Santa Cruz Biotechnology), actin (MAb 1501; Millipore; Darmstadt, Germany), CHC (MAb catalog no. 610500,

(19) A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editingeLifeOctober 10, 2014Umasankar PK, Ma L, Thieman JR, Jha A, Doray B, Watkins SC, Traub LM.611350) were from BD Transduction Laboratories (San Jose, CA). Another AP-2 α subunit mAb C-8 (1:500; sc-17771) came from Santa Cruz and the anti-Tac mAb 7 G7B6 was from Ancell (Bayport, MN). The secondary antibodies

(20) Cell-surface metalloprotease ADAM12 is internalized by a clathrin- and Grb2-dependent mechanismTraffic (Copenhagen, Denmark)November 1, 2012Stautz D, Leyme A, Grandal MV, Albrechtsen R, van Deurs B, Wewer U, Kveiborg M.

Be the First to Write a Review!

α-Adaptin 1/2 (C-8) Antibody

α-Adaptin 1/2 (C-8) Antibody from Santa Cruz Biotechnology, Inc.

Description

Santa Cruz Biotechnology, Inc.

Citations (29)

Reviews

α-Adaptin 1/2 (C-8) Antibody from Santa Cruz Biotechnology, Inc.

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map