GLT-1 Antibody PA5-17099 from Thermo Fisher Scientific

Product Specs
ItemGLT-1 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-17099
Quantity100 µL
ReactivityHuman, Mouse, Rat
NCBI Gene AliasesEIEE41, GLT-1, Eaat2, Glt, HBGT, EAAT2, MGLT1, 1700091C19Rik, 2900019G14Rik, Glt-1, DEE41, GLT1
Format0.01M HEPES with 100µg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Conjugate/TagUnconjugated
HostRabbit
ApplicationsWestern Blot
TargetGLT-1
ClonalityPolyclonal
NCBI Full Gene Namesolute carrier family 1 member 2, solute carrier family 1 (glial high affinity glutamate transporter), member 2
ImmunogenSynthetic peptide corresponding to human EAAT2
IsotypeIgG
Storage Temperature-20°C
PurityAntigen affinity chromatography
Antibody TypePrimary
Storage-20°C
Concentration22 µg/mL

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Thermo Fisher Scientific

81 Wyman Street

Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Defective Astrocyte Maturation Drives Cerebellar Neuroinflammation and DegenerationFASEB JJuly 31, 2025Karli Mockenhaupt, Masoumeh Zarei-Kheirabadi, Alexandra K. Gonsiewski, Avani Hariprashad, Lauren Dain, Johannes Verheijen, Sandeep K. Singh, Tomasz KordulaBiotech., sc‐33673, 1:1000), anti‐GLAST (Santa Cruz Biotech., sc‐365634, 1:1000), anti‐GLT1 (Invitrogen, PA5‐17099, 1:1000), or anti‐β tubulin (Santa Cruz Biotech., sc‐9104, 1:1000) antibodies diluted in TTBS buffer

(2) Modification of astrocytic Cx43 hemichannel activity in animal models of AD: modulation by adenosine A2A receptorsCellular and Molecular Life SciencesNovember 1, 2023Daniela Madeira, Joana Domingues, Cátia R. Lopes, Paula M. Canas, Rodrigo A. Cunha, Paula Agostinho(1:1000, Cell Signaling Technology Cat# 3511, RRID:AB_2110169), GLT-1 (1:1000 ThermoFisher Scientific PA5-17099 RRID:AB_10978571) GLAST (1:1000 Abcam Ab416 RRID:AB_304334), GFAP (1:20,000, Millipore Ab5804 RRID:AB_2109645)

(3) Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43(A90V) mutation display a mild reactive state and release polyP toxic to motoneuronsFrontiers in cell and developmental biologyJanuary 1, 2023Rojas F, Aguilar R, Almeida S, Fritz E, Corvalán D, Ampuero E, Abarzúa S, Garcés P, Amaro A, Diaz I, et al.monoclonal,Hum Ms,1:1000 Cx43,Invitrogen,13-8300,Mouse monoclonal,Hum Ms Rat,1:200 EAAT2,Invitrogen,PA5-17099,Rabbit polyclonal,Hum Ms Rat,1:50 GFAP,Invitrogen,MA5-15086,Mouse monoclonal,Hum Ms Rat,1:600 GFAP,Dako,z0334,Rabbit

(4) mGlu3 Metabotropic Glutamate Receptors as a Target for the Treatment of Absence Epilepsy: Preclinical and Human Genetics DataCurrent neuropharmacologyJanuary 1, 2023Celli R, Striano P, Citraro R, Di Menna L, Cannella M, Imbriglio T, Koko M, Euro Epinomics-Cogie Consortium, De Sarro G, Monn JA, et al.1:1000), GAT-1 (AB1570W, Millipore, 1:1000), GLAST (PA5-80012, ThermoFisher Scientific, 1:1000), GLT-1 (PA5-17099 ThermoFisher Scientific, 1:1000) or mouse monoclonal for GAPDH (sc-47724, Santa Cruz Biotechnology,

(5) Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneuronsNeuronMay 18, 2022Arredondo C, Cefaliello C, Dyrda A, Jury N, Martinez P, Díaz I, Amaro A, Tran H, Morales D, Pertusa M, et al.paraformaldehyde and immunostained with a rabbit polyclonal antibody against EAAT2/GLT1 (1:50; Invitrogen, Cat# PA5-17099), a mouse monoclonal antibody against Cx43 (1:200; Invitrogen, Cat# 13-8300), a rabbit polyclonal antibody

(6) SFMBT1 facilitates colon cancer cell metastasis and drug resistance combined with HMG20ACell death discoveryMay 16, 2022Pan R, Yu D, Hu J, Yang X, Wang C, Zhang L, Xue P, Sun J, Zhang X, Cai W.using Image J software. Protein expression was normalized to GAPDH. SFMBT1 (PA5-22393, 1:1000), SLC1A2 (PA5-17099, 1:1000) and HMG20A (PA5-87308, 1:1000) antibodies were purchased from Invitrogen. EZH2 (#5246, 1:1000),

(7) Low-intensity ultrasound restores long-term potentiation and memory in senescent mice through pleiotropic mechanisms including NMDAR signalingMolecular PsychiatryNovember 1, 2021Daniel G. Blackmore et al.,Cell Signaling Technology,#4858 PSD95,WB,1:1000,Merck Millipore,MABN68 Actin,WB,1:2000,Merck Millipore,MAB1501R Glt-1 (EAAT1),IHC,1:1000,ThermoFisher,PA5-17099 TRPA1,WB,1:500,Merck Millipore,ABN1009 GAP43,WB,1:1000,Merck Millipore,MAB347 Serine racemase (D5V9Z),WB,1:500,Cell Signaling Technology

(8) Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanismAnnals of neurologyJune 1, 2019Stergachis AB, Pujol-Giménez J, Gyimesi G, Fuster D, Albano G, Troxler M, Picker J, Rosenberg PA, Bergin A, Peters J, et al.transferred onto PVDF membrane prior to immunoblotting. Antibodies for immunoblots include: α-SLC1A2 (PA5–17099; Thermo Scientific); rabbit polyclonal anti-actin antibody (Santa Cruz Biotechnology); and HRP-conjugated

(9) The Hydroxyl Side Chain of a Highly Conserved Serine Residue Is Required for Cation Selectivity and Substrate Transport in the Glial Glutamate Transporter GLT-1/SLC1A2The Journal of biological chemistryDecember 18, 2015Simonin A, Montalbetti N, Gyimesi G, Pujol-Giménez J, Hediger MA.

(10) HFE polymorphisms affect cellular glutamate regulationNeurobiology of agingJune 1, 2011Mitchell RM, Lee SY, Simmons Z, Connor JR.

(11) Functional expression, purification and high sequence coverage mass spectrometric characterization of human excitatory amino acid transporter EAAT2Protein expression and purificationNovember 1, 2010Ye R, Rhoderick JF, Thompson CM, Bridges RJ.

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GLT-1 Antibody

GLT-1 Antibody from Thermo Fisher Scientific

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GLT-1 Antibody from Thermo Fisher Scientific

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