Biorbyt's APPL Rabbit mAb [KD Validated] Antibody is a Rabbit monoclonal antibody. The APPL Rabbit mAb [KD Validated] Antibody was generated using appl1 as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunohistochemistry, and Western Blot.
Description
Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway