The SMAD3 Polyclonal Antibody from Cayman Chemical is a Rabbit Polyclonal antibody. This antibody recognizes Homo Sapiens, Human, Mouse, Rat, Bovine, Canine, Non-Human Primate, and Porcine antigen. The SMAD3 Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Immunogen: Portion of amino acids 100-150 of human SMAD3
• Host: Rabbit
• Cross Reactivity: (+) Human, bovine, canine, mouse, porcine, primate, and rat
• Application(s): IF, IHC, and WB
• SMAD3 is a receptor-regulated SMAD (R-SMAD) that functions downstream of TGF-β and activin receptors and mediates their signaling. It is recruited by SARA (SMAD anchor for receptor activation) to the receptor kinase for phosphorylation. Upon phosphorylation it plays role in cell proliferation, differentiation, apoptosis and formation of ECM