Rat IgG Antibody 6-001-A from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRat IgG Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $139.00Supplier Page View Company Product Page
Catalog Number6-001-A
Quantity1 mg
TargetIgG
Conjugate/TagUnconjugated
ReactivityRat
ApplicationsControl
IsotypeIgG
HostRat
ClonalityPolyclonal
Antibody TypeIsotype Controls
Format10 mM Sodium Phosphate, 0.85% (w/v) Sodium Chloride, pH 7.2 (PBS) with 5% trehalose and 0.05% (w/v) Sodium Azide
StorageStore the unopened product at 2 - 8° C
NCBI Full Gene Nameimmunoglobulin heavy constant gamma 1 (G1m marker)

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: This product has been purified for use as normal rat IgG.

Sizes Available: 1 mg

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) The role of CXCL10 in high‐fat diet–induced skeletal muscle inflammation and atrophyJournal of Diabetes InvestigationMay 1, 2026An Liyuan, Yu Hirata, Tomoya Inoue, Kenji Sugawara, Wataru Ogawagroups. The IgG‐treated mice received intraperitoneal injections of control IgG (0.1 mg per mouse; #6‐001‐A, R&D Systems) at 3 days before initiation of HFD feeding and again at 7 days after the first injection,

(2) High mobility group box-1 protein promotes astrocytic CCL5 production through the MAPK/NF-κB pathway following spinal cord injuryScientific reportsSeptember 27, 2024Chi G, Lu J, He T, Wang Y, Zhou X, Zhang Y, Qiu L.neutralizing antibody (50 µg/kg, R&D Systems, cat. no. MAB478) or IgG control (50 µg/kg, R&D Systems, cat. no. 6-001-A) was then slowly injected (injection flow rate, 35 nl/s) intrathecally using the Hamilton syringe (needle

(3) Transwell Culture with Adipose Tissue-Derived Stem Cells and Fertilized Eggs Mimics the In Vivo Development of Fertilized Eggs to Blastocysts in the Fallopian Tube: An Animal StudyAntioxidants (Basel)June 8, 2024Toyofumi Hirakawa, Kazuhiko Nakabayashi, Noriko Ito, Kenichiro Hata, Shiori Imi, Mami Shibata, Daichi Urushiyama, Kohei Miyata, Fusanori Yotsumoto, Shin’ichiro Yasunaga, et al.Antibody Mouse VEGF Antibody (#AF-493-NA), Mouse IL-6 Antibody (#MAB406-100), Normal Rat IgG Control (#6-001-A), and Normal Goat IgG Control (#AB-108-Cmouse) were purchased from R&D Systems (Minneapolis, MN, USA).

(4) High glucose intake exacerbates experimental autoimmune prostatitis through mitochondrial reactive oxygen species-dependent TGF-β activation-mediated Th17 differentiationInternational immunopharmacologyMarch 30, 2024Niu D, Yue SY, Wang X, Li WY, Zhang L, Du HX, Liang CZ.

(5) Protective effects of macrophage-specific integrin α5 in myocardial infarction are associated with accentuated angiogenesisNature communicationsNovember 20, 2023Li R, Chen B, Kubota A, Hanna A, Humeres C, Hernandez SC, Liu Y, Ma R, Tuleta I, Huang S, et al.

(6) CD1d-dependent natural killer T-cells inactivation aggravates sepsis-induced myocardial injury via T lymphocytes infiltration and IL-6 production in miceInternational immunopharmacologyJuly 1, 2023Chen LR, Hui-Yang, Lu-Liu, Wang XX, Zhang XM, Wang HX.

(7) LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirBMolecular medicine (Cambridge, Mass.)December 12, 2022Kawaguchi Y, Matsubayashi J, Kawakami Y, Nishida R, Kurihara Y, Takei K.antibodies against goat IgG (705-585-147, Jackson ImmunoResearch, RRID: AB_2340433), purified rat IgG (6-001-A, R&D Systems, RRID: AB_10144734), peroxidase-conjugated antibodies against mouse IgG (115-035-003, Jackson ImmunoResearch

(8) IL6 supports long-term expansion of hepatocytes in vitroNature communicationsNovember 29, 2022Guo R, Jiang M, Wang G, Li B, Jia X, Ai Y, Chen S, Tang P, Liu A, Yuan Q, et al.different concentrations of control IL6 neutralizing antibody (R&D Systems, MAB406-SP) or IgG (R&D Systems, 6-001-A) as shown in Supplementary Fig. 2a–d, the medium was changed for every other day. Assessment of PI3K/AKT,

(9) Loss of IL-33 enhances elastase-induced and cigarette smoke extract-induced emphysema in miceRespiratory researchMay 15, 2021Morichika D, Taniguchi A, Oda N, Fujii U, Senoo S, Itano J, Kanehiro A, Kitaguchi Y, Yasuo M, Hanaoka M, et al.

(10) Combination of Mycobacterium indicus pranii and Heat-Induced Promastigotes Cures Drug-Resistant Leishmania Infection: Critical Role of Interleukin-6-Producing Classical Dendritic CellsInfection and immunityMay 20, 2020Dey S, Mukherjee D, Sultana SS, Mallick S, Dutta A, Ghosh J, Hussain A, Sarkar B, Mandal S, Patra P, et al.

(11) Wnt signaling contributes to withdrawal symptoms from opioid receptor activation induced by morphine exposure or chronic inflammationPainMarch 1, 2020Wu M, Li Z, Liang L, Ma P, Cui D, Chen P, Wu G, Song XJ.Frizzled-8 Fc chimera protein (Fz-8/Fc, 112-FZ), recombinant mouse Wnt-5b protein (Wnt5b, 3006-WN), and control IgG (6–001-A) were purchased from R&D Systems (Minneapolis, MN); PEG400 and DMSO were purchased from Sigma-Aldrich

(12) Blockade of IL-6 signaling prevents paclitaxel-induced neuropathy in C57Bl/6 miceCell Death & DiseaseJanuary 1, 2020Petra Huehnchen, Hannah Muenzfeld, Wolfgang Boehmerle, Matthias Endresneutralizing antibody (IL-6-AB; R&D Systems Cat# MAB406; RRID: AB_2233899) and control IgG (R&D Systems Cat# 6-001-A; RRID: AB_10144734) were prepared fresh before each treatment. All substances were injected intraperitoneally

(13) Hepatospecific ablation of p38α MAPK governs liver regeneration through modulation of inflammatory response to CCl₄-induced acute injuryScientific reportsOctober 10, 2019Fortier M, Cadoux M, Boussetta N, Pham S, Donné R, Couty JP, Desdouets C, Celton-Morizur S.

(14) The Oral Mouse Microbiome Promotes Tumorigenesis in Oral Squamous Cell CarcinomamSystemsAugust 6, 2019Stashenko P, Yost S, Choi Y, Danciu T, Chen T, Yoganathan S, Kressirer C, Ruiz-Tourrella M, Das B, Kokaras A, et al.(cytotoxic T cells), and Ly6G (neutrophils, macrophage/monocytes) or normal rat IgG (control; catalog number 6-001-A), all of which were from R&D Systems (Minneapolis, MN). Tongue sections were treated with citrate buffer,

(15) Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertensionAmerican journal of physiology. Lung cellular and molecular physiologyJune 1, 2019Udjus C, Cero FT, Halvorsen B, Behmen D, Carlson CR, Bendiksen BA, Espe EKS, Sjaastad I, Løberg EM, Yndestad A, et al.␣-antibody, 1.25 ␮g/ml, no. AF1830, R&D Systems) or an IgG control antibody (rat IgG control antibody, no. 6-001-A, R&D Systems) were added, and incubated for an additional 48 h in the presence of IL-18 before the cells

(16) Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive ImpairmentCellJanuary 10, 2019Gibson EM, Nagaraja S, Ocampo A, Tam LT, Wood LS, Pallegar PN, Greene JJ, Geraghty AC, Goldstein AK, Ni L, et al.Buffer (2% BSA/HBSS + 10 mM HEPES). Samples were blocked using rat IgG (8 μg/mL final, R&D Systems, 6–001-A) for 10 min on ice and then stained with preconjugated antibodies for 30 to 45 min. For OPC sorts, cells

(17) Batroxobin accelerated tissue repair via neutrophil extracellular trap regulation and defibrinogenation in a murine ischemic hindlimb modelPloS oneJanuary 1, 2019Masuda H, Sato A, Shizuno T, Yokoyama K, Suzuki Y, Tokunaga M, Asahara T.0.1% (v/v) BSA and 5% (v/v) goat serum at 4˚C overnight. Isotype control antibodies Purified rat IgG (#6-001-A; R&D systems, Minneapolis, MN, USA) as a control antibody was also incubated in the same manner. The

(18) Repeated water avoidance stress induces visceral hypersensitivity: Role of interleukin-1, interleukin-6, and peripheral corticotropin-releasing factorJournal of gastroenterology and hepatologyDecember 1, 2017Nozu T, Miyagishi S, Nozu R, Takakusaki K, Okumura T.

(19) IL-17A Produced by Innate Lymphoid Cells Is Essential for Intestinal Ischemia-Reperfusion InjuryJournal of immunology (Baltimore, Md. : 1950)October 15, 2017Geha M, Tsokos MG, Bosse RE, Sannikova T, Iwakura Y, Dalle Lucca JJ, De Waal Malefyt R, Tsokos GC.

(20) T Cell-Derived Granulocyte-Macrophage Colony-Stimulating Factor Contributes to Dry Eye Disease Pathogenesis by Promoting CD11b+ Myeloid Cell Maturation and MigrationInvestigative ophthalmology & visual scienceFebruary 1, 2017Dohlman TH, Ding J, Dana R, Chauhan SK.either 2.5 μg/mL of anti–GM-CSF neutralizing antibody (505407; BioLegend) or rat immunoglobulin G (IgG 6-001-A; R&D Systems, Inc.) for 4 hours. During this incubation period, bone marrow from the femurs and tibias

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Rat IgG Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Rat IgG Antibody from R&D Systems, a Bio-Techne Brand

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