Bioss Inc.'s EGFRvIII Polyclonal Antibody, RBITC Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The EGFRvIII Polyclonal Antibody, RBITC Conjugated was generated using EGFR, and epidermal growth factor receptor as the antigen and it reacts with Homo Sapiens, and Human.
Description
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]