CXCL10 Polyclonal Antibody bs-1502R from Bioss Inc.

Product Specs
ItemCXCL10 Polyclonal Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-1502R
Molecular Weight10kDa
ImmunogenKLH conjugated peptide, mouse CXCL10
Conjugate/TagUnconjugated
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
ReactivityHuman, Mouse, Rat, Rat, Mouse, Human
ClonalityPolyclonal
Antibody TypePrimary Antibody
IsotypeIgG
Quantity100ul, 20uL
ApplicationsIF(IHC-P), IHC-P, IF(ICC), ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), IHC
HostRabbit
TargetCXCL10
Concentration1ug/ul
NCBI Gene AliasesgIP-10, INP10, IP10, IP-10, mob-1, Ifi10, CRG-2, C7, Scyb10
NCBI Full Gene Namechemokine (C-X-C motif) ligand 10
Tissuebrain, vagina

Questions and Answers

Can this antibody be used for immunohistochemistry in cancer research?

Yes, the CXCL10 Polyclonal Antibody has been utilized in immunohistochemistry, as demonstrated in studies investigating the tumor microenvironment in cervical cancer, where it was applied to formalin-fixed paraffin-embedded tissue sections to analyze CXC chemokine expression ().

What role does CXCL10 play in immune responses according to recent studies?

CXCL10 is involved in regulating immune cell transport and activity, particularly in the context of inflammation and tumor immunity. It has been shown to influence macrophage polarization in acute pancreatitis, suggesting its significance in modulating immune responses during inflammatory conditions ().

Is there evidence supporting the use of this antibody in flow cytometry applications?

Yes, the CXCL10 Polyclonal Antibody has been cited in flow cytometry applications, where it was used to assess immune cell populations and their responses in various experimental models, including studies on myocardial ischemia/reperfusion injury ().

What species can this antibody react with, and how has it been validated in research?

The CXCL10 Polyclonal Antibody is reactive with mouse, human, and rat tissues. Its effectiveness has been validated in multiple studies, including those examining CXCL10 expression in various disease contexts, such as cervical cancer and acute pancreatitis, where it was shown to correlate with immune cell infiltration and disease progression (, ).

Bioss Inc.

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Suite 4610

Woburn, MA 01801

United States

Phone: 800.501.7654 (Toll free)
Phone: +1.781.569.5821 (International)

Email: info@biossusa.com
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Company Profile

Website: www.biossusa.com

(1) CXCL10 secreted by SPRY1-deficient epidermal keratinocytes fuels joint inflammation in psoriatic arthritis via CD14 signalingJournal of Clinical InvestigationAugust 1, 2025Fan Xu, Ying-Zhe Cui, Xing-Yu Yang, Yu-Xin Zheng, Xi-Bei Chen, Hao Zhou, Zhao-Yuan Wang, Yuan Zhou, Yi Lu, Ying-Ying Li, et al.for 1 hour at room temperature. Subsequently, cells were incubated with anti-CXCL10 antibody (Bioss, bs-1502R, 1:100) and anti-CD14 antibody (Abcam, ab221678, 1:1,000) overnight at 4°C and then incubated with corresponding

(2) The Cardioprotective Role of Neutrophil-Specific STING in Myocardial Ischemia/Reperfusion InjurybioRxivSeptember 14, 2024Maegan L. Brockman, Triniti A. Scruggs, Lanfang Wang, Gabriella Kabboul, John W. Calvert, Rebecca D. LevitViolet 711,Biolegend 139311,1:50 CD206,PE-Fire 700,Biolegend 141741,1:100 CXCL10,Alexa Fluor 594,Bioss bs-1502R-594,1:100 IFNα,FITC,Pblassays 22100–3,1:100 Ly6G,APC-Fire 750,Biolegend 127651,1:50 pIRF3,APC,Cell Signaling

(3) Pathoimmunological analyses of fatal E11 infection in premature infantsFrontiers in cellular and infection microbiologyJanuary 1, 2024Luo W, Wang L, Chen Z, Liu M, Zhao Y, Wu Y, Huang B, Wang P.slides underwent DAPI staining. Specifically, these slides were incubated with anti-IP10 antibody (#bs-1502R; Bioss; China) for 30 min and then treated with anti-rabbit/mouse horseradish peroxidase (HRP)–conjugated

(4) Amino acid catabolite markers for early prognostication of pneumonia in patients with COVID-19Nature communicationsDecember 20, 2023Maeda R, Seki N, Uwamino Y, Wakui M, Nakagama Y, Kido Y, Sasai M, Taira S, Toriu N, Yamamoto M, et al.Prosurfactant Protein C (catalog #H00006440-M01; Novus Biologicals, Centennial, CO, USA) and CXCL10 (catalog #BS-1502R; Bioss, Woburn, MA, USA), each diluted 1:500 in 1x PBS. Secondary antibodies were two Alexa Fluor-conjugated

(5) MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10Cell death & diseaseFebruary 24, 2023Peng C, Tu G, Wang J, Wang Y, Wu P, Yu L, Li Z, Yu X.(ab222320, used in western blot) were purchased from Abcam (Shanghai, China). Amylase (bs-4030R) and CXCL10 (bs-1502R) were purchased from Bioss (Beijing, China). iNOS (13120) and p-RIPK3 (91702, used in immunofluorescence

(6) Identification of Genes Potentially Associated with Melanoma Tumorigenesis Through Co-Expression Network AnalysisInternational Journal of General MedicineNovember 19, 2021Xiuyun Xuan, Yuqi Wang, Yanhong Sun, Changzheng Huanganti-CCL5 antibody (bs-1324R, Bioss, China), anti-CXCL9 antibody (bs-2551R, Bioss, China) and anti-CXCL10 (bs-1502R, Bioss, China) at 4°C overnight. After being washed with PBS (pH 7.6), the slides were treated with

(7) Analysis of therapeutic targets and prognostic biomarkers of CXC chemokines in cervical cancer microenvironmentCancer Cell InternationalJuly 28, 2021Weina Kong, Gang Zhao, Haixia Chen, Weina Wang, Xiaoqian Shang, Qiannan Sun, Fan Guo, Xiumin Maantibodies composed of rabbit anti-CXCL9 antibody (bs-2551R [Bioss], 1:100), rabbit anti-CXCL10 antibody (bs-1502R [Bioss], 1:150), rabbit anti-CXCL11 antibody (DF9917 [Affinity], 1:150) and rabbit anti-CXCL13 antibody

(8) Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stressMolecular cellMay 20, 2021Zhang W, Liu W, Jia L, Chen D, Chang I, Lake M, Bentolila LA, Wang CY.anti-CXCL9,R&D Systems,Cat#AF-492-NA; RRID: AB_2086734 Rabbit polyclonal anti-CXCL10,Bioss Antibodies,Cat#BS-1502R; RRID: AB_10859700 Mouse monoclonal anti-IP10,Santa Cruz,Cat#sc-101500; RRID: AB_1564138 Rabbit polyclonal

(9) Cordycepin Attenuates IFN-γ-Induced Macrophage IP-10 and Mig Expressions by Inhibiting STAT1 Activity in CFA-Induced Inflammation Mice ModelInflammationApril 1, 2020Yang R, Wang X, Xi D, Mo J, Wang K, Luo S, Wei J, Ren Z, Pang H, Luo Y.

(10) Key features and homing properties of NK cells in the liver are shaped by activated iNKT cellsScientific reportsNovember 8, 2019Trittel S, Chambers BJ, Heise U, Guzmán CA, Riese P.blocking solution (Zytomed Systems). For the staining of liver sections, the primary antibody anti IP-10 (bs-1502R, Bioss) and a secondary biotinylated antibody (Zytomed Systems) were used. Subsequently, streptavidin–HRP

(11) Establishment of a chronic obstructive pulmonary disease mouse model based on the elapsed time after LPS intranasal instillationLaboratory animal researchMarch 1, 2018Lee SY, Cho JH, Cho SS, Bae CS, Kim GY, Park DH.Abnova, Taipei, Taiwan), CXCL-1 (PAB8798,; Abnova), CXCL-9 (bs-2551R; Bioss, Woburn, MA, USA), CXCL-10 (bs-1502R; Bioss), and CXCL-11 (bs-2552R; Bioss). The slides were incubated for 10 min with biotinylated secondary

(12) Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibilityPloS oneJanuary 1, 2018Henschel AM, Cabrera SM, Kaldunski ML, Jia S, Geoffrey R, Roethle MF, Lam V, Chen YG, Wang X, Salzman NH, et al.anti-Ccl11 Abs (R&D Systems, #AF-420-NA), or rabbit polyclonal anti-Cxcl10 Abs (Bioss, Atlanta, GA, USA, #bs-1502R) in combination with mouse monoclonal anti-insulin Abs (Sigma-Aldrich). Secondary staining was accomplished

(13) Platelet-cytokine Complex Suppresses Tumour Growth by Exploiting Intratumoural Thrombin-dependent Platelet AggregationScientific reportsApril 27, 2016Li YT, Nishikawa T, Kaneda Y.FITC-conjugated anti-PF4 antibody (Biorbyt Ltd., orb13908) and AF350-conjugated anti-IP10 antibody (Bioss, bs-1502R-AF350) were used. For dense granule staining, an unconjugated anti-CD63 antibody (Abcam, MX-49.129.5)

(14) An innate antiviral pathway acting before interferons at epithelial surfacesNature immunologyFebruary 1, 2016Iversen MB, Reinert LS, Thomsen MK, Bagdonaite I, Nandakumar R, Cheshenko N, Prabakaran T, Vakhrushev SY, Krzyzowska M, Kratholm SK, et al.

(15) Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like DiseaseCancer immunology researchAugust 1, 2015Clancy-Thompson E, Perekslis TJ, Croteau W, Alexander MP, Chabanet TB, Turk MJ, Huang YH, Mullins DW.

(16) Tissue-Specific Regulation of p38α-Mediated Inflammation in Con A-Induced Acute Liver DamageJournal of immunology (Baltimore, Md. : 1950)May 15, 2015Kang YJ, Bang BR, Otsuka M, Otsu K.

(17) Defective removal of ribonucleotides from DNA promotes systemic autoimmunityThe Journal of clinical investigationJanuary 1, 2015Günther C, Kind B, Reijns MA, Berndt N, Martinez-Bueno M, Wolf C, Tüngler V, Chara O, Lee YA, Hübner N, et al.

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CXCL10 Polyclonal Antibody

CXCL10 Polyclonal Antibody from Bioss Inc.

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Bioss Inc.

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CXCL10 Polyclonal Antibody from Bioss Inc.

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