The SCAP/SREBF chaperone protein Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to SCAP, and SREBF chaperone. This antibody recognizes Mouse, and Rat antigen. The SCAP/SREBF chaperone protein Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs