TNF alpha Polyclonal Antibody from Bioss Inc.

Supplier Page

Supplier Page from
Bioss Inc. for
TNF alpha Polyclonal Antibody

The TNF alpha Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to TNF, and Tumor necrosis factor. This antibody recognizes Human, Mouse, Rat, Horse, and Rabbit antigen. The TNF alpha Polyclonal Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.

Description

Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells