Aggrecan core protein Antibody bs-1223R from Bioss Inc.

Product Specs
ItemAggrecan core protein Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-1223R
Molecular Weight79/250kDa
ImmunogenKLH conjugated peptide, human Aggrecan core protein
ApplicationsIHC, WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), IHC-P, WB
Antibody TypePrimary Antibody
ClonalityPolyclonal
IsotypeIgG
Quantity100ul, 20uL
Conjugate/TagUnconjugated
ReactivityMouse, Rat, Rat, Mouse, Human, Rabbit
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
TargetAggrecan core protein 1
HostRabbit
Concentration1ug/ul
NCBI Gene AliasesCSPG1, SSOAOD, CSPGCP, MSK16, AGC1, AGCAN, SEDK
NCBI Full Gene Nameaggrecan
Tissuenuclei pulposi, cartilage

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Bioss Inc.

300 Tradecenter Drive

Suite 4610

Woburn, MA 01801

United States

Phone: 800.501.7654 (Toll free)
Phone: +1.781.569.5821 (International)

Email: info@biossusa.com
orders@biossusa.com
support@biossusa.com
sales@biossusa.com

Company Profile

Website: www.biossusa.com

(1) Ultrasound-responsive CPS piezoelectric hydrogel synergistically repairs annulus fibrosus defects through immune reprogramming and cell recruitmentMaterials Today BioApril 1, 2026Huajun Pan, Chengzhi Liang, Shuihua Ding, Peichuan Xu, Changxiong Cai, Chongzhi Pan, Wei Xiong, Haiyan Li, Xinxin Miao, Xigao Chengtreated with the test hydrogels under ultrasonic stimulation. ECM production was using Aggrecan (Bioss, BS-1223R) and Collagen I (Bioss, BS-0578R) probes, and the staining was observed under a fluorescent inverted

(2) Runx1 overexpression induces early onset of intervertebral disc degenerationAgingSeptember 8, 2025Fukunaga T, Diaz-Hernandez ME, Heller JG, Zhang C, Drissi H.Cell signaling technology, 12434), CAIII (dilution ratio 1:200, Proteintech, 15197-1-AP), Aggrecan (1:200, Bioss, BS-1223R), ADAMTS5(dilution ratio 1:100, Abcam, ab41037), collagen II (dilution 1:200, ROXKLAND, 600401104),

(3) Leptin receptor signaling mediates the distinct tendon–bone interface reconstruction in rotator cuff tears and osteoporosis-comorbid rotator cuff tearsStem Cell Res TherAugust 22, 2025Dongxu Zhu, Xinrui Zhu, Yingze Zhang, Xiaohong HuangAffinity biosciences, USA), Adiponectin (Adipoq, 1:500, bs-0471R, Bioss, China), Aggrecan (Acan, 1:500, bs-1223R, Bioss), Lep (1:500, ER1912-27, HUABIO), Angptl4 (1:500,ER1903-68, HUABIO), Lepr (1:500, ET1704-44,

(4) Amniotic fluid MSCs for scaffold-free cartilage repair: spheroid fusion and chondrogenic microtissue developmentFuture Sci OAJune 11, 2025Carolina Coli Zuliani, Jéssica Bruna da Cunha, Victor Marchiori de Souza, Kleber Cursino de Andrade, Ângela Maria Moraes, Ibsen Bellini Coimbrawith rabbit polyclonal anti-Type II Collagen (bs-0709R - BIOSS®) and mouse polyclonal anti-Aggrecan (bs-1223R - BIOSS®) antibodies. Subsequently, sections were treated with HiDef Detection™ HRP Polymer System (Cell

(5) Inhibiting synovial inflammation and promoting cartilage repair in rheumatoid arthritis using a matrix metalloproteinase-binding hydrogelMaterials Today BioJune 1, 2025Zhanpeng Xue, Nan Li, Kaijun Du, Jianxiong Shu, Zhenwen Huang, Zhifei Gao, Xiaobo Xie, Qi Li, Yao Luantibody of MMP-9 (ET1704-69-100, HUABIO), TNF-α (ER65189, HUABIO), Col-2 (ab308455, ABCAM), and ACAN (bs-1223R, BIOSS) at 4 °C for 12 h. All primary antibody were diluted by 1:100. After an additional 1 h at room

(6) NOXA exacerbates endoplasmic-reticulum-stress-induced intervertebral disc degeneration by activating apoptosis and ECM degradationCell Death DiscovMay 28, 2025Zhiming Liu, Hui Lu, Xianjuan Zhang, Shuai Tang, Antao Lin, Shuo Han, Xuexiao MaProteintech, Wuhan, China), Cleaved Caspase-3 (25128-1-AP, 1:1000, Proteintech, Wuhan, China), ACAN (bs-1223R, 1:1000, Bioss, Beijing, China), COL2 (bs-5881R, 1:1000, Bioss, Beijing, China), GAPDH (10494-1-AP,

(7) CKLF1 interference alleviates IL‑1β‑induced inflammation, apoptosis and degradation of the extracellular matrix in chondrocytes via CCR5Experimental and Therapeutic MedicineMay 9, 2023Haoran Wang, Zhongqing Wu, Kanna Xucat. no. ab9485) antibodies were all purchased from Abcam, while the anti-aggrecan (1/1,000; cat. no. bs-1223R) antibody was obtained from BIOSS. On the following day, the membranes were incubated with HRP-conjugated

(8) PHLPP1 deficiency protects against age‐related intervertebral disc degenerationJOR SPINEDecember 1, 2022Changli Zhang, Katherine M. Joseph, Nazir M. Khan, Martha Elena Diaz‐Hernandez, Hicham Drissi, Svenja Illien‐JungerVector Laboratories). Samples were then incubated with primary antibodies against ADAMTS5 (ab41037, ABCAM), aggrecan (BS‐1223R, Bioss), KRT19 (TROMA‐III, DSHB), FOXO1 (2880, cell signaling) and FOXO3a (2497, cell signaling). After

(9) Comparison of the differentiation abilities of bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells toward nucleus pulposus-like cells in three-dimensional cultureExperimental and therapeutic medicineSeptember 1, 2021Dai X, Guan Y, Zhang Z, Xiong Y, Liu C, Li H, Liu B.anti-GLUT1 antibody (1:1,000; cat. no. bs-20173R; BIOSS), rabbit anti-aggrecan antibody (1:1,000; cat. no. bs-1223R; BIOSS), mouse anti-collagen II antibody (1:1,000; cat. no. bsm-33409M; BIOSS) and rabbit anti-β-actin

(10) Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in miceCell death & diseaseOctober 3, 2019Zhang C, Smith MP, Zhou GK, Lai A, Hoy RC, Mroz V, Torre OM, Laudier DM, Bradley EW, Westendorf JJ, et al.samples were incubated for 1 h at room temperature with an anti-aggrecan antibody (1:200 dilution, bs-1223R, Bioss Antibodies Inc, MA, USA). Next, samples were incubated with the secondary, alkaline phosphatase-conjugated

(11) Interleukin-1 receptor antagonist protein (IL-1Ra) and miR-140 overexpression via pNNS-conjugated chitosan-mediated gene transfer enhances the repair of full-thickness cartilage defects in a rabbit modelBone & joint researchMarch 1, 2019Zhao R, Wang S, Jia L, Li Q, Qiao J, Peng X.

(12) Aspirin-Mediated Attenuation of Intervertebral Disc Degeneration by Ameliorating Reactive Oxygen Species In Vivo and In VitroOxidative medicine and cellular longevityJanuary 1, 2019Liu Y, Lin J, Wu X, Guo X, Sun H, Yu B, Shen J, Bai J, Chen Z, Yang H, et al.UK). Anti-β-actin and 4 ′ ,6-diamidino2-phenylindole (DAPI) were purchased from Beyotime. Aggrecan (bs-1223R), ADAMTS-4 (bs-4191R), and ADAMTS-5 (bs-3573R) were purchased from Bioss (Beijing, China). 2.4. NPC

(13) Leukemia inhibitory factor promotes extracellular matrix synthesis in degenerative nucleus pulposus cells via MAPK-ERK1/2 signaling pathwayBiochemical and biophysical research communicationsDecember 9, 2018Zhou H, Shen J, Hu Z, Zhong X.

(14) miR-1307-3p suppresses the chondrogenic differentiation of human adipose-derived stem cells by targeting BMPR2International journal of molecular medicineDecember 1, 2018Yang Z, Li R, Ao J, Wa QD, Zhang Y, Chen L, Wen J, Chen B, Pan W, Li B, et al.

(15) Optimization of puncture injury to rat caudal disc for mimicking early degeneration of intervertebral discJournal of orthopaedic research : official publication of the Orthopaedic Research SocietyJanuary 1, 2018Hu MH, Yang KC, Chen YJ, Sun YH, Lin FH, Yang SH.

(16) Effect of Choline on the Composition and Degradation Enzyme of Extracellular Matrix of Mice Chondrocytes Exposed to FluorideBiological trace element researchFebruary 1, 2017Zhao Y, Hao J, Wang J, Wang J.

(17) Lentivirus-mediated TGF-β3, CTGF and TIMP1 gene transduction as a gene therapy for intervertebral disc degeneration in an in vivo rabbit modelExperimental and therapeutic medicineApril 1, 2016Liu Y, Yu T, Ma XX, Xiang HF, Hu YG, Chen BH.follows: Monoclonal rabbit anti‑collagen‑II (1:100; bs‑0709R), monoclonal rabbit anti‑aggrecan (1:100; bs‑1223R) and monoclonal mouse anti‑glyceraldehyde‑3‑phosphate dehydrogenase (GAPDH; 1:500; bsm‑0978M). Following

(18) Mesenchymal stem cell characteristics of dental pulp and periodontal ligament stem cells after in vivo transplantationBiomaterialsAugust 1, 2014Lei M, Li K, Li B, Gao LN, Chen FM, Jin Y.

(19) Treatment of rabbit intervertebral disc degeneration with co-transfection by adeno-associated virus-mediated SOX9 and osteogenic protein-1 double genes in vivoInternational journal of molecular medicineNovember 1, 2013Ren S, Liu Y, Ma J, Liu Y, Diao Z, Yang D, Zhang X, Xi Y, Hu Y.

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IHC-P

Aggrecan core protein Antibody

Aggrecan core protein Antibody from Bioss Inc.

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Bioss Inc.

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Aggrecan core protein Antibody from Bioss Inc.

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