Aquaporin 4 Polyclonal Antibody bs-0634R from Bioss Inc.

Product Specs
ItemAquaporin 4 Polyclonal Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-0634R
Molecular Weight36kDa
NCBI Gene AliasesWCH4
ImmunogenKLH conjugated peptide, mouse AQP4
ApplicationsWB, FCM, WB, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
ClonalityPolyclonal
Antibody TypePrimary Antibody
ReactivityHuman, Mouse, Rat, Mouse
IsotypeIgG
Quantity100ul, 20uL
Conjugate/TagUnconjugated
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
HostRabbit
TargetAquaporin 4
Concentration1ug/ul
NCBI Full Gene Nameaquaporin 4
TissueBrain, Jejunum, brain

Questions and Answers

Can this antibody be used to study the role of Aquaporin 4 in brain injury models?

Yes, the Aquaporin 4 Polyclonal Antibody has been utilized in studies investigating its role in neonatal hypoxic-ischemic brain injury. For instance, research demonstrated that silencing AQP4 expression promoted axonal growth in oxygen-glucose deprivation neurons, indicating its involvement in neurobehavioral recovery following brain injury ().

What experimental techniques can I use this antibody with?

The Aquaporin 4 Polyclonal Antibody is suitable for various applications, including Western Blotting, Immunofluorescence, Immunocytochemistry, and Immunohistochemistry. These techniques have been employed to detect AQP4 expression in different tissues, such as the cortex and hippocampus, particularly in studies involving neonatal rats ().

Is this antibody effective for detecting AQP4 in both human and rodent tissues?

Yes, this antibody has been shown to react with AQP4 in multiple species, including humans, mice, and rats. This broad reactivity allows for comparative studies across species, which is beneficial for translational research in understanding AQP4's role in various physiological and pathological contexts.

How does the use of this antibody contribute to understanding axonal regeneration?

The Aquaporin 4 Polyclonal Antibody has been implicated in studies that reveal the relationship between AQP4 expression and axonal regeneration. For example, AQP4 knockout models showed enhanced axonal growth and improved neurological outcomes, suggesting that targeting AQP4 may be a potential strategy for promoting recovery after brain injuries ().

Bioss Inc.

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Woburn, MA 01801

United States

Phone: 800.501.7654 (Toll free)
Phone: +1.781.569.5821 (International)

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Company Profile

Website: www.biossusa.com

(1) Integrated multi omics and machine learning reveal mitochondrial immunometabolic networks in sepsis associated encephalopathyScientific reportsSeptember 29, 2025Zhang Z, Qiu X, Zeng X, Liu X, Lu J, Xu C, Huang J, Zhao C, Zhan Y.Beijing Zhongshan Golden Bridge Biotechnology (ZSGB-BIO, China); Rabbit Polyclonal Anti-AQP4 (cat. no. bs-0634R) and Rabbit Polyclonal Anti-HPA (cat. no. bs-25726R) were purchased from Bioss (China); Rabbit Polyclonal

(2) AQP4 knockout promotes neurite outgrowth via upregulating GAP43 expression in infant rats with hypoxic‐ischemic brain injuryIbrainSeptember 1, 2022Qi‐Qin Dan, Zheng Ma, Ya‐Xin Tan, Belegu Visar, Li Chentemperature. After that, samples were incubated at 4°C for 18 h with anti‐AQP4 antibody (rabbit, 1:100, bs‐0634R, Bioss), Tuj1 (mouse, 1:100, 2326315, Millipore), and then washed three times in 0.01 mol/L PBS for

(3) Melatonin lowers edema after spinal cord injuryNeural regeneration researchDecember 15, 2014Li C, Chen X, Qiao S, Liu X, Liu C, Zhu D, Su J, Wang Z.

(4) Detection of hypoxic-ischemic brain injury with 3D-enhanced T2* weighted angiography (ESWAN) imagingEuropean journal of radiologyNovember 1, 2013QiangQiang Gang, Jianing Zhang, Peng Hao, Yikai Xu

(5) The role of neuropeptide Y and aquaporin 4 in the pathogenesis of intestinal dysfunction caused by traumatic brain injuryThe Journal of surgical researchOctober 1, 2013Hubin Duan, Chunyan Hao, Yimin Fan, Hongqin Wang, Yueting Liu, Jiehe Hao, Cuiping Xu, Xiaodong Liu, Huaping Zhang

(6) Hypertonic saline reduces lipopolysaccharide-induced mouse brain edema through inhibiting aquaporin 4 expressionCrit CareOctober 4, 2012Cao C, Yu X, Liao Z, Zhu N, Huo H, Wang M, Ji G, She H, Luo Z, Yue S.

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Aquaporin 4 Polyclonal Antibody

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Aquaporin 4 Polyclonal Antibody from Bioss Inc.

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Aquaporin 4 Polyclonal Antibody from Bioss Inc.

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