The CD3 epsilon Polyclonal Antibody, PerCP Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to CD3E. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The CD3 epsilon Polyclonal Antibody, PerCP Conjugated has been shown to work in the following applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]