MyBioSource.com's TXNIP Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, and Western Blot. The TXNIP Polyclonal Antibody was generated using TXNIP as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
This gene encodes a thioredoxin-binding protein that is member of the alpha arrestin protein family. Thioredoxin is thiol-oxidoreductase that is major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants