MyBioSource.com's Anti-Hu CD142 APC monoclonal antibody. The Anti-Hu CD142 APC Antibody was generated using F3 as the antigen. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: Cell Sorting, Isolation, Flow Cytometry, and Immunofluorescence.
Description
CD142, also known as coagulation factor III, tissue thromboplastin, and tissue factor. It is a transmembrane glycoprotein, which enables cells to initiate the blood coagulation cascades, and functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. It is the only one factor in the coagulation pathway for which a congenital deficiency has not been described