MyBioSource.com's Ubiquitin Protein Ligase E3A Rabbit mAb is a Rabbit monoclonal antibody. The Ubiquitin Protein Ligase E3A Rabbit mAb Antibody was generated using UBE3A, and ubiquitin protein ligase E3A as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot.
Description
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B