The Anti-BCMA [CA8] Antibody from MyBioSource.com Monoclonal antibody to CENPE. This antibody recognizes Homo Sapiens, Human, and Non-Human Primate antigen. The Anti-BCMA [CA8] Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Flow Cytometry.
Description
The original mouse parental antibody 118G03 was generated by immunizing SJL mice with recombinant human BCMA/TNFRSF17-Fc chimera (R&D 193-Fc) by using the RIMMS method (Rapid immunization multiple sites). A chimeric version of this antibody was generated and it is called CA8.
Discusses the novel immunotherapy treatment for multiple myelomas by targeting a cell surface protein like B-cell maturation antigen.
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques