MyBioSource.com's PTPMT1 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The PTPMT1 Polyclonal Antibody was generated using protein tyrosine phosphatase mitochondrial 1, and Ptpmt1 as the antigen and it reacts with Mouse.
Description
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP to phosphatidylglycerol (PG (By similarity. PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle (By similarity. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production (By similarity. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues (By similarity. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity. May prevent intrinsic apoptosis, probably by regulating mitochondrial membrane integrity