The PACS1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PACS1. This antibody recognizes Homo Sapiens, and Human antigen. The PACS1 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance