The Rabbit Anti-TGF beta Receptor III/TGFBR3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TGFBR3. This antibody recognizes Homo Sapiens, and Human antigen. The Rabbit Anti-TGF beta Receptor III/TGFBR3 Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, and Western Blot.
Description
Betaglycan also known as Transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate/heparan sulfate proteoglycan >300 kDa in molecular weight. This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene