MerTK (B-1) Antibody sc-365499 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMerTK (B-1) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-365499
Hostmouse
Conjugate/TagUnconjugated
Quantity200 µg/ml
NCBI Gene Aliasesc-mer, c-Eyk, Eyk, MER, nmf12, Nyk, Mer, RP38, Tyro12
CloneB-1
ClonalityMonoclonal
ApplicationsWB, IP, IF, ELISA
Reactivitymouse, rat, human
Antibody TypePrimary Antibodies
NCBI Full Gene NameMER proto-oncogene, tyrosine kinase, MER proto-oncogene tyrosine kinase
TargetMerTK
FormatPurified
IsotypeIgG2b

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Hypoxic migrasomes drive colorectal cancer liver metastasis by mediating CD5L+ macrophage efferocytosis via NRP2/PROX1 axisJ Transl MedDecember 8, 2025Yuqi Luo, Yiwen Huang, Yaoxing Huang, Longzhen Chen(1:200, ab182422, Abcam), NRP2 (1:250, #3366, CST), PROX1(1:250, sc-81983, Santa cruz), MERTK (200 µg/mL, sc-365499, Santa Cruz). After washing off unbound primary antibodies, the sample was incubated with a fluorophore-conjugated

(2) CXCL12/CXCR4 modulates macrophage efferocytosis to induce glomerular crescent formation and fibrosis via ELMO1/DOCK180/RAC1 signaling in ANCA-associated glomerulonephritisCellular and molecular life sciences : CMLSJuly 19, 2025Liu Z, Deng Y, Song X, Cai X, Xiong H, Tan L, Wei S, Li Q, Wang X, Jiang W, et al.,Santa Cruz,sc-20060 CD86,1:500,ABclonal,A1199 CXCR4,1:100,Abcam,ab124824 CXCR4,2ug/mL,NOVUS,NBP1-77067 CXCR4,2ug/mL,Invitrogen,PA5-19856 MERTK,1:500,Santa Cruz,sc-365499 ELMO1,1:500,Santa Cruz,sc-271519 DOCK1(DOCK180),1:500,ABclonal,A17359 RAC1,1:500,Proteintech,66122–1-Ig TGF-β1,1:1000,Abcam,ab215715 Antibodies

(3) Tumor-associated MerTK promotes a pro-inflammatory microenvironment and enhances immune checkpoint inhibitor response in triple-negative breast cancerFront OncolMay 5, 2025Bridget E. Crossman, Regan L. Harmon, Mari Iida, Jillian M. Adams, Candie Y. Lin, Christine E. Glitchev, Terry D. Juang, Sheena C. Kerr, Roxana A. Alexandridis, Meredith Hyun, et al.0.3% Triton X-100, and blocked in normal goat serum. Cells were stained with MerTK primary antibody (sc-365499, Santa Cruz Biotechnologies, Dallas, TX, USA) overnight at 4C. Cells were then stained with a secondary

(4) PCSK9 attenuates efferocytosis in endothelial cells and promotes vascular agingTheranosticsJanuary 1, 2023Liu S, Wu J, Stolarz A, Zhang H, Boerma M, Byrum SD, Rusch NJ, Ding Z.were incubated with primary antibody recognizing either PCSK9 (Abcam, ab31762), MerTK (Santa Cruz, sc-365499), eNOS (Cell Signaling, 32027S), NLRP3 (Cell Signaling, 15101S), IL-1β (Cell Signaling, 12703S), NF-κB

(5) Phagocytosing differentiated cell-fragments is a novel mechanism for controlling somatic stem cell differentiation within a short time frameCellular and molecular life sciences : CMLSOctober 6, 2022Wakao S, Oguma Y, Kushida Y, Kuroda Y, Tatsumi K, Dezawa M.

(6) Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complexCell reportsJuly 19, 2022Wu X, Sosunov AA, Lado W, Teoh JJ, Ham A, Li H, Al-Dalahmah O, Gill BJA, Arancio O, Schevon CA, et al.,Santa Cruz Biotechnology,Cat# sc-133061; RRID:AB_2202075 Mouse anti-MerTK,Santa Cruz Biotechnology,Cat# sc-365499; RRID:AB_10843860 Rabbit anti-GPC4,Proteintech,Cat# 13048-1-AP; RRID:AB_10640157 Goat anti-SPACL1/Hevin,R and D Systems

(7) Effects of RGD-grafted phosphatidylserine-containing liposomes on the polarization of macrophages and bone tissue regenerationBiomaterialsDecember 1, 2021Wu L, Kim Y, Seon GM, Choi SH, Park HC, Son G, Kim SM, Lim BS, Yang HC.

(8) KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathwayCell death and differentiationApril 1, 2021Du W, Zhu J, Zeng Y, Liu T, Zhang Y, Cai T, Fu Y, Zhang W, Zhang R, Liu Z, et al.

(9) Tumour-Secreted Protein S (ProS1) Activates a Tyro3-Erk Signalling Axis and Protects Cancer Cells from ApoptosisCancersNovember 22, 2019Al Kafri N, Hafizi S.

(10) Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast CancerCancer researchMay 15, 2019Kasikara C, Davra V, Calianese D, Geng K, Spires TE, Quigley M, Wichroski M, Sriram G, Suarez-Lopez L, Yaffe MB, et al.

(11) MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathwayeLifeFebruary 8, 2019Xu H, Xu SJ, Xie SJ, Zhang Y, Yang JH, Zhang WQ, Zheng MN, Zhou H, Qu LH.RRID:AB_325417",WB (1:3000) Antibody,"Mouse anti-MERTK, (B-1) mouse mAb",Santa Cruz Biotechnology,"Cat. #: sc-365499, RRID:AB_10843860",WB (1:2000) Antibody,"Rabbit anti-FGFR1, (D8E4) Rabbit mAb",Cell signaling,"Cat.

(12) Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cellsPloS oneJanuary 1, 2019Santamaria-Barria JA, Zeng S, Greer JB, Beckman MJ, Seifert AM, Cohen NA, Zhang JQ, Crawley MH, Green BL, Loo JK, et al.probed with antibodies against phospho-Mer (ab192649, 1:500 dilution; Abcam, Cambridge, UK), total Mer (sc365499, 1:200 dilution; Santa Cruz Biotechnology, Dallas, TX), phospho-STAT3 (Ser727; Y705, 1:1000 dilution;

(13) A dynamic N⁶-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitorsCell researchNovember 1, 2018Yan F, Al-Kali A, Zhang Z, Liu J, Pang J, Zhao N, He C, Litzow MR, Liu S.Cell Signaling #2865), anti-β-Actin (1:1000, Santa Cruz #sc-47778), anti-MERTK (1:1000, Santa Cruz #sc-365499), anti-FTO (1:2000, AdipoGen #AG-20A-0064), anti-METTL3 (1:2000, Proteintech #15073-1-AP), anti-ALKBH5

(14) Circulating apoptotic bodies maintain mesenchymal stem cell homeostasis and ameliorate osteopenia via transferring multiple cellular factorsCell researchSeptember 1, 2018Liu D, Kou X, Chen C, Liu S, Liu Y, Yu W, Yu T, Yang R, Wang R, Zhou Y, et al.anti-mouse TSP1 (sc-95886), anti-mouse αvβ3(sc-6627), antimouse αvβ5 (sc-13588), anti-mouse MerTK (sc-365499) anti-mouse FasL (C-178), anti-mouse OPG (H-249), anti-mouse RANKL (FL-317) and anti-mouse frizzled

(15) Association between Genetic Variations of MERTK and Chronic Obstructive Pulmonary Disease in KoreansJournal of Korean medical scienceFebruary 12, 2018Kim WJ, Park HJ, Choi YJ, Kwon EY, Kim BM, Lee JH, Chang JH, Lee Kang J, Choi JH.blocking, the membranes were incubated with the following primary antibodies: a mouse anti-MERTK antibody (sc-365499; Santa Cruz Biotechnology, Santa Cruz, CA, USA), or a goat anti-β-actin antibody (sc-1616; Santa Cruz Biotechnology

(16) Irf8 regulates the progression of myeloproliferative neoplasm-like syndrome via Mertk signaling in zebrafishLeukemiaJanuary 1, 2018Zhao F, Shi Y, Huang Y, Zhan Y, Zhou L, Li Y, Wan Y, Li H, Huang H, Ruan H, et al.

(17) MerTK inhibition by RXDX-106 in MerTK activated gastric cancer cell linesOncotargetDecember 1, 2017Kim JE, Kim Y, Li G, Kim ST, Kim K, Park SH, Park JO, Park YS, Lim HY, Lee H, et al.Danvers, MA, USA), Axl (#8661, CST), p-MerTK (Y281+Y749, ab192649, Abcam, Cambridge, MA, USA), MerTK (SC-365499, Santa Cruz, Dallas, TX, USA), p-Erk (#9102, CST), Erk (#4370, CST), p-AKT (#4060, CST), AKT (#9272,

(18) Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cellsMolecular visionJanuary 1, 2017Samuel W, Jaworski C, Postnikova OA, Kutty RK, Duncan T, Tan LX, Poliakov E, Lakkaraju A, Redmond TM.Abcam: ab137304), anti-mouse bestrophin (1:5,000, Abcam: ab2182), anti-mouse MERTK (1:1,000, Santa Cruz: SC-365499), anti-mouse Tyrosinase (1:1,000, Santa Cruz: SC-20035), anti-rabbit E-cadherin mAb (1:1,000, Cell Signaling:

(19) Induction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein KinaseFrontiers in cell and developmental biologyJanuary 1, 2016Richter E, Ventz K, Harms M, Mostertz J, Hochgräfe F.(Santa Cruz #sc-961), anti-MEK4 (Santa Cruz #sc-837), anti-CaMK1 (abcam #ab68234), anti-MerTK (Santa Cruz #sc-365499), anti-CDK1 (abcam # ab18). Bound primary antibodies were detected using fluorophore-conjugated secondary

(20) Coordinated expression of tyro3, axl, and mer receptors in macrophage ontogenyMacrophageJanuary 1, 2016Malawista A, Wang X, Trentalange M, Allore HG, Montgomery RR.processed for immunoblotting. Immunoblots were probed with anti-MerTK (B-1) (Santa Cruz Biotechnology, TX sc-365499), anti-Axl (R & D AF154), anti-Tyro3 (A-7) (Santa Cruz sc-166359), and anti-β-actin (Cell Signaling,

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MerTK (B-1) Antibody

MerTK (B-1) Antibody from Santa Cruz Biotechnology, Inc.

Santa Cruz Biotechnology, Inc.

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MerTK (B-1) Antibody from Santa Cruz Biotechnology, Inc.

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