VWF (C-12) Antibody sc-365712 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemVWF (C-12) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-365712
Hostmouse
Quantity200 µg/ml
ClonalityMonoclonal
CloneC-12
Conjugate/TagUnconjugated
NCBI Gene AliasesB130011O06Rik, VWD, 6820430P06Rik, C630030D09, F8VWF
ApplicationsWB, IP, IF, ELISA
Reactivitymouse, rat, human
Antibody TypePrimary Antibodies
NCBI Full Gene NameVon Willebrand factor, von Willebrand factor
TargetVWF
FormatPurified
IsotypeIgG1

Questions and Answers

Can this antibody be used to study von Willebrand factor in liver sinusoidal endothelial cells during liver fibrosis?

Yes, the VWF (C-12) Antibody has been utilized in studies examining the expression of von Willebrand factor in liver sinusoidal endothelial cells, particularly in the context of liver fibrosis. For instance, it was used in immunohistochemical analysis to assess the expression of von Willebrand factor in rat models of liver fibrosis, demonstrating its relevance in this area of research ().

Is this antibody effective for immunofluorescence applications in endothelial cell studies?

The VWF (C-12) Antibody has been shown to work effectively in immunofluorescence applications. It has been employed to detect von Willebrand factor in various studies, including those focusing on endothelial cells, where it contributed to understanding the cellular mechanisms involved in conditions like acute lung injury and liver fibrosis (, ).

What species can this antibody react with, and is it suitable for cross-species studies?

The VWF (C-12) Antibody is reactive with mouse, human, and rat species. This broad reactivity makes it suitable for cross-species studies, allowing researchers to investigate the role of von Willebrand factor across different models, including human and animal studies (, ).

Has this antibody been cited in significant research related to liver diseases?

Yes, the VWF (C-12) Antibody has been cited in numerous scientific articles, with a total of 55 citations. It has been referenced in studies investigating liver diseases, including liver fibrosis and the mechanisms of endothelial dysfunction, highlighting its importance in this field of research (, ).

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Transplantation of human neural stem cells repairs neural circuits and restores neurological function in the stroke-injured brainNeural Regeneration ResearchMarch 1, 2026Peipei Wang, Peng Liu, Yingying Ding, Guirong Zhang, Nan Wang, Xiaodong Sun, Mingyue Li, Mo Li, Xinjie Bao, Xiaowei Chenwe used von Willebrand factor (vWF; mouse monoclonal antibody, 1:100, Santa Cruz Biotechnology, Cat# sc-365712, RRID: AB_10842026) and Ki67 rabbit monoclonal antibody (1:500, Abcam, Cat# ab16667, RRID: AB_302459)

(2) Plasmodium falciparum impairs Ang-1 secretion by pericytes in a 3D brain microvessel modelEMBO Molecular MedicineOctober 16, 2025Rory K M Long, François Korbmacher, Paolo Ronchi, Hannah Fleckenstein, Martin Schorb, Waleed Mirza, Mireia Mallorquí, Ruth Aguilar, Gemma Moncunill, Yannick Schwab, et al.saline (PBS)). Primary antibodies including rabbit anti-αSMA-555 (EPR5368, Abcam), mouse anti-vWF (sc-365712, Santa Cruz), mouse anti-CD31 (ab215911, Abcam), mouse anti-ZO-1 (10017242, Invitrogen,), rabbit anti-β-catenin

(3) DMP1-mediated transformation of DPSCs to CD31+/CD144+ cells demonstrate endothelial phenotype both in vitro and in vivoFront Cell Dev BiolAugust 8, 2025Amudha Ganapathy, Yinghua Chen, Velavan Bakthavachalam, Anne Georgeblocking with 5% BSA in PBS for 1 h. Primary antibodies against CD31 (ab28364, Abcam, Cambridge, MA), vWF (SC 365712, Santa Cruz Biotechnology, Dallas, TX), and FN (F3648, Sigma Aldrich), were added and incubated for

(4) ADAMTS13 Improves Endothelial Function and Reduces Inflammation in Diabetic RetinopathyCellsJanuary 9, 2025Ahmed M. Abu El-Asrar, Mohd I. Nawaz, Ajmal Ahmad, Mairaj Siddiquei, Eef Allegaert, Lowie Adyns, Lotte Vanbrabant, Priscilla W. Gikandi, Gert De Hertogh, Sofie Struyf, et al.with the following reagents and conditions: VWF with a mouse monoclonal anti-VWF antibody (1:1000, sc-365712, Santa Cruz Biotechnology Inc., Santa Cruz, CA, USA), CD41 with a mouse monoclonal anti-CD41 antibody

(5) Catechol-rich gelatin microspheres as restorative medical implants intended for inhibiting seroma formation and promoting wound healingMaterials Today BioDecember 1, 2024Xinping Wang, Guoqing Wang, Jianfei Wang, Junqiang Xue, Gaoli Liu, Changjiang Fanprimary antibody against collagen type I (Col1, A24112, ABclonal, China) and von Willebrand Factor (vWF, sc-365712, Santa Cruz) for 1 h at 37 °C, washed thrice with PBS, and incubated with 5 μg/mL of Goat Anti-rabbit

(6) Transplantation of human neural stem cells repairs neural circuits and restores neurological function in the stroke-injured brainNeural Regen ResNovember 13, 2024Peipei Wang, Peng Liu, Yingying Ding, Guirong Zhang, Nan Wang, Xiaodong Sun, Mingyue Li, Mo Li, Xinjie Bao, Xiaowei Chenwe used von Willebrand factor (vWF; mouse monoclonal antibody, 1:100, Santa Cruz Biotechnology, Cat# sc-365712, RRID: AB_10842026) and Ki67 rabbit monoclonal antibody (1:500, Abcam, Cat# ab16667, RRID: AB_302459)

(7) Dentin matrix protein 1 and HUVEC-ECM scaffold promote the differentiation of human dental pulp stem cells into endothelial lineage: implications in regenerative medicineFrontiers in PhysiologyJuly 8, 2024Amudha Ganapathy, Karthikeyan Narayanan, Yinghua Chen, Cassandra Villani, Anne Georgeantibodies against CD31 and VE-Cadherin (CD144) (ab28364, ab33168, Abcam, Cambridge, MA), vWF, GRP78 (sc-365712, sc-166490, Santa Cruz Biotechnology, Dallas, TX) and VEGR2 (rabbit, #2479, Cell Signaling Technology)

(8) Polydopamine (PDA) coatings with endothelial vascular growth factor (VEGF) immobilization inhibiting neointimal formation post zinc (zn) wire implantation in rat aortasBiomaterials researchSeptember 4, 2023Fu J, Zhu Q, Chen Z, Zhao J, Wu S, Zhao M, Xu S, Lai D, Fu G, Zhang W.

(9) Tanshinone I alleviates steroid-induced osteonecrosis of femoral heads and promotes angiogenesis: in vivo and in vitro studiesJournal of orthopaedic surgery and researchJune 30, 2023Sun K, Xue Y, Zhang X, Li X, Zhao J, Xu X, Zhang X, Yang F.DF8614, Affinity, China), CD31 (1:100-diluted, 66,065-2-Ig, Proteintech, China), VWF (1:50-diluted, sc-365712, Santa Cruz, USA) and RUNX family transcription factor 2 (RUNX2; 1:50-diluted, 20,700-1-AP, Proteintech)

(10) Expansion of macrophage and liver sinusoidal endothelial cell subpopulations during non-alcoholic steatohepatitis progressioniScienceMay 19, 2023Shen Z, Shen B, Dai W, Zhou C, Luo X, Guo Y, Wang J, Xu X, Sun Z, Cai X, et al.RRID:AB_2927461 Itgad/Cd11d,Abbexa,Cat# abx101639; RRID: AB_2927460 CD31,Abcam,Cat# ab222783; RRID: AB_2905525 vWF,Santa Cruz,Cat# sc-365712; RRID: AB_10842026 Egr1,Santa Cruz,Cat# sc-101033; RRID: AB_1122474 ,, "Chemicals, peptides, and

(11) Delta Opioid Peptide Targets Brain Microvascular Endothelial Cells Reducing Apoptosis to Relieve Hypoxia-Ischemic/Reperfusion InjuryPharmaceuticsDecember 23, 2022Zhang R, Chen M, Deng Z, Kong L, Shen B, Zhang L.

(12) Nucleophagic Degradation of Progerin Ameliorates Defenestration in Liver Sinusoidal Endothelium Due to SIRT1-Mediated Deacetylation of Nuclear LC3CellsDecember 3, 2022Bai Y, Liu J, Jiang X, Li X, Zhang B, Luo X.and Methods 2.1. Antibodies and Reagents The primary antibodies included anti-vWF (Santa Cruz, #sc-365712), anti-COL 1A1 (Proteintech, #14695-1-AP), anti-progerin (Santa Cruz, #sc-81611), anti-Lamin A/C (Cell Signaling Technology

(13) Maresin 1 intervention reverses experimental pulmonary arterial hypertension in miceBritish journal of pharmacologyNovember 1, 2022Li H, Li X, Hao Y, Wu C, Fu Y, Su N, Chen H, Ying B, Wang H, Su L, et al.

(14) Hypoxic preconditioning improves the survival and pro-angiogenic capacity of transplanted human umbilical cord mesenchymal stem cells via HIF-1α signaling in a rat model of bronchopulmonary dysplasiaBiochemical and biophysical research communicationsMay 21, 2022Hao C, You J, Qiu H, Zhou O, Liu J, Zou W, Yang K, Fu Z, Zou L.

(15) Nitric oxide regulates adhesiveness, invasiveness, and migration of anoikis-resistant endothelial cellsBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicasJanuary 1, 2022Mesquita APS, Matsuoka M, Lopes SA, Pernambuco Filho PCA, Cruz AS, Nader HB, Lopes CC.(Abcam, cat# ab87213, RRID:AB_1951498); mouse anti-von Willebrand factor (1:100) (Santa Cruz, cat# sc-365712, USA); and mouse anti-β-actin (1:5000) (Cell Signaling, cat# 3700, RRID:AB_2242334) diluted in blocking

(16) URB597 and Andrographolide Improve Brain Microvascular Endothelial Cell Permeability and Apoptosis by Reducing Oxidative Stress and Inflammation Associated with Activation of Nrf2 Signaling in Oxygen-Glucose DeprivationOxidative medicine and cellular longevityJanuary 1, 2022Wang DP, Kang K, Sun J, Lin Q, Lv QL, Hai J.Immunofluorescence Staining Immunofluorescence staining was used to detect the expression of vWF (No. sc-365712, Santa Cruz Biotechnology, Dallas, Texas, USA), ZO-1, Occludin, and Nrf2. First, using 4% paraformaldehyde,

(17) Trigonella foenum-graecum L. and Psoralea corylifolia L. Improve Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats through Suppression of Oxidative StressEvidence-based complementary and alternative medicine : eCAMJanuary 1, 2022Jiang S, Cai Q, Gao Y, Dong H, Zhao Y, Wu F, Ba X, Luan Y, Zou X, Xu L, et al.Ltd. (Wuhan, China). Rabbit anti-p47phox(p47) (sc-17845), anti-(Bcl-2) (sc-7382), and anti- (vWF) (sc-365712) were purchased from Santa Cruz Biotechnology. Rat anti-α-SMA (19245S), anti-Bax (2772S), anti-eNOS

(18) Ubiquitinated ligation protein NEDD4L participates in MiR-30a-5p attenuated atherosclerosis by regulating macrophage polarization and lipid metabolismMolecular therapy. Nucleic acidsDecember 3, 2021Song F, Li JZ, Wu Y, Wu WY, Wang Y, Li G.(MA5-35185) monoclonal antibodies were from Thermo Fisher Scientific, anti-von Willebrand factor (vWF) (SC-365712), anti-α-smooth muscle actin (SC-53142), and anti-actin (SC-8432) were obtained from Santa Cruz, and

(19) New Blood-Brain Barrier Models Using Primary Parkinson's Disease Rat Brain Endothelial Cells and Astrocytes for the Development of Central Nervous System Drug Delivery SystemsACS chemical neuroscienceOctober 20, 2021Cai P, Zheng Y, Sun Y, Zhang C, Zhang Q, Liu Q.

(20) Neuronal CD200 Signaling Is Protective in the Acute Phase of Ischemic StrokeStrokeOctober 1, 2021Al Mamun A, Ngwa C, Qi S, Honarpisheh P, Datar S, Sharmeen R, Xu Y, McCullough LD, Liu F.(1:500, R&D Systems, MN, USA), rat anti-CD200 (1:300, abcam, USA), mouse anti-von Willebrand Factor (VWF, sc-365712, Santa Cruz biotechnology Inc, TX, USA), and rabbit anti-glial fibrillary acidic protein (GFAP) (1:500,

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VWF (C-12) Antibody

VWF (C-12) Antibody from Santa Cruz Biotechnology, Inc.

Questions and Answers

Santa Cruz Biotechnology, Inc.

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VWF (C-12) Antibody from Santa Cruz Biotechnology, Inc.

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