Phospho-FRA1 (Ser265) (D22B1) Rabbit mAb 5841S from Cell Signaling Technology

Product Specs
ItemPhospho-FRA1 (Ser265) (D22B1) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number5841S
Quantity100 µl
ApplicationsW, ChIP, C&R
ReactivityH, M, R
TargetFRA1 (Ser265) phosphate
IsotypeIgG
ModificationsFRA1 (Ser265) phosphate
HostRabbit
CloneD22B1
Molecular Weight40
NCBI Gene AliasesFRA, FRA1, fra-1
ClonalityMonoclonal
NCBI Full Gene NameFOS like 1, AP-1 transcription factor subunit
Research AreaMAP Kinase Signaling

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuitNatureJanuary 7, 2026Vladislav Pokatayev, Alok Jaiswal, Angela R. Shih, Åsa Segerstolpe, Bihua Li, Elizabeth A. Creasey, Yanhua Zhao, Crystal Lin, Shane Murphy, Chih-Hung Chou, et al.14-4714-82), Flag antibody (MilliporeSigma, catalogue no. F1804-200UG), FOSL1 antibody (Cell Signaling, 5841S) or TEAD1 antibody (Active Motif, catalogue no. 61643) was used. Once the DNA pellets had been resuspended

(2) PARP7 and aryl hydrocarbon receptor differentially regulate mammary cancer cell proliferation and STING-induced type I interferon signallingCell Oncol (Dordr)December 23, 2025Ninni E. Olafsen, Samaneh S. Åhrling, Marit Rasmussen, Linnea A. M. Erlingsson, Emma N. Granly, Akinori Takaoka, Jason MatthewsD9J7L), anti-IRF9 (Cell Signalling Technology; D9I5H), anti-pFOSL1 (S265) (Cell Signalling Technology; 5841S), anti-FOSL1 (C-12) (Santa Cruz Biotechnology, Dallas, TX, USA; sc-28310), anti-CASP3 (Cell Signalling

(3) Fosl1 is a transcriptional effector of BRAF V600E-driven intestinal tumorigenesisiScienceNovember 21, 2025Zakia Alam, Rebecca Nightingale, Analia Lesmana, Cheng Liu, Laura J. Jenkins, Mark F. Richardson, Lawrence Croft, Ian Y. Luk, Camilla M. Reehorst, Fiona Chionh, et al.anti-Ki67 Thermo Fisher Scientific, MA5-14520) or anti-phospo-FOSL1 (Cell Signaling Technologies; Cat# 5841) antibodies. The slides were then washed with TBST and incubated with Dako envision anti-rabbit labeled

(4) Cell state plasticity emerging from co-regulated, competitive, and configurable interactions within the AP-1 networkbioRxivNovember 10, 2025Yonatan N. Degefu, Magda Bujnowska, Douglas G. Baumann, Mohammad Fallahi-Sichaniab124722, RRID: AB_11001005" Phospho-FRA1 (Ser265) (D22B1) Rabbit mAb,Cell Signaling Technologies,"Cat# 5841, RRID: AB_10835210" Fra2 (D2F1E) Rabbit mAb,Cell Signaling Technologies,"Cat# 19967, RRID: AB_2722526" c-Jun (60A8) Rabbit mAb

(5) The Discovery of Small ERK5 Inhibitors via Structure-Based Virtual Screening, Biological Evaluation and MD SimulationsMoleculesOctober 25, 2025Noor Atatreh, Radwa E. Mahgoub, Rose Ghemrawi, Molham Sakkal, Nour Sammani, Mostafa Khair, Mohammad A. Ghattas1:700 dilution, including Phospho-c-Fos (#5348, Cell Signalling, Danvers, MA, USA), Phospho-FRA1 (#5841, Cell Signalling, USA), Phospho-CREB (#9198, Cell Signalling, USA), and GAPDH (#2118, Cell Signalling,

(6) CRISPR–Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP -Deleted CancerCancer ResearchSeptember 15, 2025Nikola Knoll, Sarah Masser, Blanka Bordas, Richard Y. Ebright, Guangyan Li, Devishi Kesar, Eliana Destefanis, Nicholas Kania, Diego J. Rodriguez, Jayu Jen, et al.RRID:AB_477629; and the following antibodies from Cell Signaling Technology: Phospho-FRA1 (Ser 265) (5841S) RRID:AB_10835210, SDMA (13222S) RRID:AB_2714013, P21/Waf1/Cip1 (2947T) RRID:AB_823586, Phospho-Rb (8516S)

(7) CRISPR-Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP-deleted cancerCancer ResSeptember 15, 2025Nikola Knoll, Sarah Masser, Blanka Bordas, Richard Y. Ebright, Guangyan Li, Devishi Kesar, Eliana Destefanis, Nicholas Kania, Diego J. Rodriguez, Jayu Jen, et al.RRID:AB_477629; and the following antibodies from Cell Signaling Technology: Phospho-FRA1 (Ser 265) (5841S) RRID:AB_10835210, SDMA (13222S) RRID:AB_2714013, P21/Waf1/Cip1 (2947T) RRID:AB_823586, Phospho-Rb (8516S)

(8) Granulosa cell expression of Fos is critical for regulating ovulatory gene expressions in the mouse ovaryThe FASEB JournalFebruary 28, 2025Jacqueline Southall, Shawn Park, Yohan Choi, Hayce Jeon, Chemyong Ko, Misung Joprotein,14283,Western Blot (1:1000),"Rabbit, IgG",Monoclonal,Phospho-FRA1 (Ser265) (D22B1) Rabbit mAb,"Cell Signaling, #5841" FOSL2,synthetic peptide corresponding to residues surrounding Val245 of human Fra2 protein,14284,"Western Blot

(9) Granulosa cell expression of Fos is critical for regulating ovulatory gene expressions in the mouse ovaryFASEB JFebruary 28, 2025Jacqueline Southall, Shawn Park, Yohan Choi, Hayce Jeon, Chemyong Ko, Misung Joprotein,14283,Western Blot (1:1000),"Rabbit, IgG",Monoclonal,Phospho-FRA1 (Ser265) (D22B1) Rabbit mAb,"Cell Signaling, #5841" FOSL2,synthetic peptide corresponding to residues surrounding Val245 of human Fra2 protein,14284,"Western Blot

(10) FOSL1 transcriptionally dictates the Warburg effect and enhances chemoresistance in triple-negative breast cancerJ Transl MedJanuary 2, 2025Gang Zhao, Yutong Liu, Shiqi Yin, Runxiang Cao, Qian Zhao, Yifan Fu, Ye Ducollected. The immunoprecipitation of DNA was carried out overnight at 4 °C using anti-phospho-FOSL1 (#5841, Cell Signaling Technology) or an isotype-matched control IgG from the sonicated lysates. Subsequently,

(11) FRA1 controls acinar cell plasticity during murine Kras(G12D)-induced pancreatic acinar to ductal metaplasiaDevelopmental cellNovember 18, 2024Li AL, Sugiura K, Nishiwaki N, Suzuki K, Sadeghian D, Zhao J, Maitra A, Falvo D, Chandwani R, Pitarresi JR, et al.sc-376148 ; RRID:AB_11012022 Phospho-FRA1 (Ser265) (D22B1) Rabbit mAb,Cell Signaling Technology,Cat# 5841; RRID:AB_10835210 c-Jun (60A8) Rabbit mAb,Cell Signaling Technology,Cat# 9165; RRID:AB_2130165 Phospho-c-Jun (Ser63) II Antibody

(12) Novel PROTAC probes targeting FOSL1 degradation to eliminate head and neck squamous cell carcinoma cancer stem cellsBioorganic chemistryOctober 1, 2024Zaman SU, Pagare PP, Huang B, Rilee G, Ma Z, Zhang Y, Li J.antibodies were used in the immunofluorescence study: anti-phospho-FOSL1 (Cell Signaling Technology, #5841) and anti-FOSL1 (Abcam, #232745). Animal Survival Study For survival study, ×106 UM-SCC-1 cells mixed

(13) PTEN Lipid Phosphatase Activity Suppresses Melanoma Formation by Opposing an AKT/mTOR/FRA1 Signaling AxisCancer researchFebruary 1, 2024Xu X, Bok I, Jasani N, Wang K, Chadourne M, Mecozzi N, Deng O, Welsh EA, Kinose F, Rix U, et al.(CST, #9101), 4E-BP1 (CST, #9452), phospho-4E-BP1 (Ser65) (CST, #9451), phospho-FRA1 (Ser 265) (CST, #5841). β-Actin (Invitrogen, AM4302) (1:3,000) was blotted as a loading control. Membranes were washed 3 times

(14) PTEN Lipid Phosphatase Activity Suppresses Melanoma Formation by Opposing an AKT/mTOR/FRA1 Signaling AxisCancer ResearchFebruary 1, 2024Xiaonan Xu, Ilah Bok, Neel Jasani, Kaizhen Wang, Manon Chadourne, Nicol Mecozzi, Ou Deng, Eric A. Welsh, Fumi Kinose, Uwe Rix, et al.(CST, #9101), 4E-BP1 (CST, #9452), phospho-4E-BP1 (Ser65) (CST, #9451), phospho-FRA1 (Ser 265) (CST, #5841). β-Actin (Invitrogen, AM4302) (1:3,000) was blotted as a loading control. Membranes were washed 3 times

(15) Fra-1 induces apoptosis and neuroinflammation by targeting S100A8 to modulate TLR4 pathways in spinal cord ischemia/reperfusion injuryBrain pathology (Zurich, Switzerland)January 1, 2023Chen Y, Dong Y, Zhang ZL, Han J, Chen FS, Tong XY, Ma H.ultrasonically fragmented chromatin. Chromatin was immunoprecipitated using a ChIP‐grade antibody against Fra‐1 (5841, Cell Signaling Technology). Then, the cross‐links in the protein‐DNA complexes were broken, and the

(16) MET-Induced CD73 Restrains STING-Mediated Immunogenicity of EGFR-Mutant Lung CancerCancer researchNovember 2, 2022Yoshida R, Saigi M, Tani T, Springer BF, Shibata H, Kitajima S, Mahadevan NR, Campisi M, Kim W, Kobayashi Y, et al.catalog no. 4060), FRA1 (Abcam, catalog no. 124722), phospho-FRA1 (Cell Signaling Technology, catalog no. 5841), cGAS(Cell Signaling Technology, catalog no. 15102), and β-actin (Cell Signaling Technology, catalog

(17) AP-1 transcription factor network explains diverse patterns of cellular plasticity in melanoma cellsCell reportsAugust 2, 2022Comandante-Lou N, Baumann DG, Fallahi-Sichani M.ab124722, RRID: AB_11001005" Phospho-FRA1 (Ser265) (D22B1) Rabbit mAb,Cell Signaling Technologies,"Cat# 5841, RRID: AB_10835210" Fra2 (D2F1E) Rabbit mAb,Cell Signaling Technologies,"Cat# 19967, RRID: AB_2722526" c-Jun (60A8) Rabbit mAb

(18) The AXL-PYK2-PKCα axis as a nexus of stemness circuits in TNBCLife science allianceJune 1, 2021Khera L, Vinik Y, Maina F, Lev S.purchased from Santa Cruz Biotechnology. Antibodies to pSMAD3 (9520), SMAD3 (9523), pFAK (8556), pFRA1 (5841), Oct4 (2750S), and Nanog (3580S) were purchased from Cell Signaling Technologies. Antibodies to CD44

(19) A Novel Lens for Cell Volume Regulation: Liquid-Liquid Phase SeparationCellular Physiology and BiochemistryApril 21, 2021Shunya Ishihara, Hidenori Ichijo, Kengo WatanabePharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan) Tel. +81-3-5841-4858, Fax +81-3-5841-4798, E-Mail ichijo@mol.f.u-tokyo.ac.jp; kwatanabe@15.alumni.u-tokyo.ac.jp 135 Physiol

(20) Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK InhibitionCancersApril 13, 2021Catalano A, Adlesic M, Kaltenbacher T, Klar RFU, Albers J, Seidel P, Brandt LP, Hejhal T, Busenhart P, Röhner N, et al.Danvers, MA, USA, 4695S), anti- phospho- FRA1 (Ser265) (D22B1) (1:1000, Cell Signaling, Danvers, MA, USA, 5841), anti-FRA1 (D80B4) (1:1000, Cell Signaling, Danvers, MA, USA, 5281), anti-BRAF/Raf-B (H-145) (1:2000,

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Phospho-FRA1 (Ser265) (D22B1) Rabbit mAb

Phospho-FRA1 (Ser265) (D22B1) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-FRA1 (Ser265) (D22B1) Rabbit mAb from Cell Signaling Technology

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