Iscalimab HY-P99670 from MedChemExpress | Biocompare.com

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Iscalimab

Description

Iscalimab (CFZ-533) is a non-depleting IGg1 monoclonal antibody targeting CD40 (K_D: 0.3 nM). Iscalimab can be used for research of Graves' hyperthyroidism and autoimmune diseases

Product Specs
ItemIscalimab
CompanyMedChemExpress
Price $450.00Supplier Page View Company Product Page
Catalog NumberHY-P99670
TypeChemical
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity1 mg
Purity99.64%
Research AreaMetabolic Disease; Inflammation/Immunology

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(1) Immunosuppression Profile of CFZ533 (Iscalimab), a Non-Depleting Anti-CD40 Antibody, and the Presence of Opportunistic Infections in a Rhesus Monkey Toxicology StudyToxicologic pathologyJuly 1, 2022Flandre TD, Mansfield KG, Espié PJ, Rubic-Schneider T, Ulrich P.

(2) A Novel Anti-CD40 Monoclonal Antibody, Iscalimab, for Control of Graves Hyperthyroidism-A Proof-of-Concept TrialThe Journal of clinical endocrinology and metabolismMarch 1, 2020Kahaly GJ, Stan MN, Frommer L, Gergely P, Colin L, Amer A, Schuhmann I, Espie P, Rush JS, Basson C, et al.

(3) Characterization of the in vitro and in vivo properties of CFZ533, a blocking and non-depleting anti-CD40 monoclonal antibodyAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsDecember 1, 2018Ristov J, Espie P, Ulrich P, Sickert D, Flandre T, Dimitrova M, Müller-Ristig D, Weider D, Robert G, Schmutz P, et al.

(4) A novel, blocking, Fc-silent anti-CD40 monoclonal antibody prolongs nonhuman primate renal allograft survival in the absence of B cell depletionAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsNovember 1, 2015Cordoba F, Wieczorek G, Audet M, Roth L, Schneider MA, Kunkler A, Stuber N, Erard M, Ceci M, Baumgartner R, et al.

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