MyBioSource.com's Anti-Hu CD271 APC is a Mouse monoclonal antibody. The Anti-Hu CD271 APC Antibody was generated using NGFR as the antigen. It reacts with Human, Feline, Non-Human Primate, Rabbit, and Other Mammalian. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells