The Anti-CXCR3 antibody (DM208), Rabbit mAb from MyBioSource.com is a Rabbit Monoclonal antibody. This antibody recognizes Human antigen. The Anti-CXCR3 antibody (DM208), Rabbit mAb has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Flow Cytometry.
Description
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]