MyBioSource.com's Anti-Hu CD274 APC is a Mouse monoclonal antibody. The Anti-Hu CD274 APC Antibody was generated using CD274 as the antigen. It reacts with Human, and Non-Human Primate. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its ligand CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor(s) for CD274 is likely