MyBioSource.com's Anti-Hu CD46 APC is a Mouse monoclonal antibody. The Anti-Hu CD46 APC Antibody was generated using CD46, and CD46 molecule as the antigen. It reacts with Human, and Bovine. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa