The GBA Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GBA. This antibody recognizes Human, and Rat antigen. The GBA Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants