Fig 2: Establishment of the animal model. A Flowchart of the mouse modeling cycle. B-C Changes in colon length between the Con and Mod groups (n = 5). D HE and Masson staining of mouse colons from the Con and Mod groups. E-J IHC staining of α-SMA, COL I, IL1RN, MUC1, and SERPINA1 in the colons of mice from the Con and Mod groups (n = 3). (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)