Description
Product Characteristics: DNA repair protein RAD51 homolog 2 antibody, hREC2 antibody, MGC34245 antibody, OTTHUMP00000212251 antibody, OTTHUMP00000212253 antibody, OTTHUMP00000212254 antibody, OTTHUMP00000212255 antibody, R51H2 antibody, RA51B_HUMAN antibody, RAD51 homolog B (S. cerevisiae) antibody, RAD51 homolog B antibody, RAD51 like 1 antibody, RAD51 like protein 1 antibody, RAD51-like protein 1 antibody, Rad51B antibody, RAD51L1 antibody, REC2 antibody, RecA like protein antibody, Recombination repair protein antibody
Target Information: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Jul 2011]