The Anti-PCNA PE Antibody from MyBioSource.com is a Mouse Monoclonal antibody to PCNA, and proliferating cell nuclear antigen. This antibody recognizes Human, Mouse, Rat, Chicken/Bird, Drosophila/Arthropod, and Non-Human Primate antigen. The Anti-PCNA PE Antibody has been shown to work in the following applications: Flow Cytometry.
Description
PCNA (proliferating cell nuclear antigen), which is the DNA polymerase delta auxiliary protein acting in homotrimeric form to increase the processivity of leading strand synthesis during DNA replication. PCNA is expressed in the nucleus of all proliferating cells. In response to DNA damage, it is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. PCNA is a useful marker of DNA synthesis, as its form not involved in DNA synthesis degradates in histological preparations in the presence of organic solvents