MyBioSource.com's Anti-Hu CD66e APC is a Mouse monoclonal antibody. The Anti-Hu CD66e APC Antibody was generated using CEA cell adhesion molecule 5, and CEACAM5 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
The CD66e (CEA; 180-200 kDa) is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3). Human CD66e is heavily glycosylated GPI anchored protein capable of both homophilic and heterophilic adhesion.Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells. CD66e is found in serum and it is clinically used as a tumor marker for early detection of disease due to its expression in adenocarcinomas - potential target of tumor imaging and drug targeting