The CD7 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CD7. This antibody recognizes Human antigen. The CD7 Antibody has been shown to work in the following applications: Flow Cytometry, Immunohistochemistry, and Western Blot.
Description
CD7 (also designated T cell leukemia antigen) is a type I transmembrane glycoprotein that is expressed on pluripotential hemapoietic cells, most human thymocytes and some peripheral blood T cells. CD7 is a marker for pluripotential stem cell leukemias and T cell acute lymphocytic leukemia. A role for CD7 in the activation of T cells with g/d receptors has been suggested. CD8 T cells from patients infected with HIV-1 displayed profound down-modulation of CD7 expression as compared with healthy subjects. CD7 is among the pan-T-cell antigens down-regulated in acute infectious mononucleosis