The Anti-Ms CD26 Purified Antibody from MyBioSource.com is a Rat Monoclonal antibody to DPP4. This antibody recognizes Mouse antigen. The Anti-Ms CD26 Purified Antibody has been shown to work in the following applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry - frozen, and Immunoprecipitation.
Description
CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus