The Rabbit Anti-Spliceosome RNA Helicase DDX39B Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to DDX39B. This antibody recognizes Human antigen. The Rabbit Anti-Spliceosome RNA Helicase DDX39B Antibody has been shown to work in the following applications: Other.
Description
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway