The BubR1 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to BUB1B. This antibody recognizes Human antigen. The BubR1 Rabbit mAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot.
Description
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]