The AChE Polyclonal Antibody from Bioassay Technology Laboratory is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, and Rat antigen. The AChE Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Acetylcholinesterase hydrolyzes the neurotransmitter: acetylcholine at neuromuscular junctions and brain cholinergic synapses: and thus terminates signal transmission. It is also found on the red blood cell membranes: where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties: but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene: and the structural diversity in the gene products arises from alternative mRNA splicing: and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain: muscle and other tissues is the hydrophilic species: which forms disulfide-linked oligomers with collagenous: or lipid-containing structural subunits. The other: alternatively