Bioassay Technology Laboratory's DCTN3 Rabbit Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
This gene encodes the smallest subunit of dynactin: a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions: including ER-to-Golgi transport: the centripetal movement of lysosomes and endosomes: spindle formation: cytokinesis: chromosome movement: nuclear positioning: and axonogenesis. This subunit: like most other dynactin subunits: exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil: and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants