MAP LC3β (G-2) Antibody sc-271625 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMAP LC3β (G-2) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-271625
ClonalityMonoclonal
NCBI Gene Aliases1010001C15Rik, MAP1A/1BLC3, MAP1LC3B-a, 4922501H04Rik, ATG8F, LC3B, MAP1A/MAP1B, LC3a, ATG8G, LC3b, Atg8, 1010001H21Rik, Map1lc3, LC3
ApplicationsWB, IP, IF, IHC(P), ELISA
Conjugate/TagUnconjugated
Antibody TypePrimary Antibodies
Quantity200 µg/ml
Reactivitymouse, rat, human
CloneG-2
Hostmouse
NCBI Full Gene Namemicrotubule associated protein 1 light chain 3 beta 2, microtubule associated protein 1 light chain 3 beta, microtubule-associated protein 1 light chain 3 alpha, microtubule-associated protein 1 light chain 3 beta
TargetMAP LC3beta
FormatPurified
IsotypeIgG2b

Questions and Answers

What applications has the MAP LC3β antibody been used for in scientific research?

The MAP LC3β antibody has been shown to work in various applications including Western Blotting, Immunofluorescence, Immunohistochemistry, and Immunoprecipitation, as evidenced by its use in studies examining autophagy markers in different experimental contexts, such as testicular ischemia and glioblastoma models.

Can this antibody be used to study autophagy in rat models?

Yes, the MAP LC3β antibody has been utilized in rat models, as demonstrated in studies investigating autophagy during testicular ischemia and reperfusion injury, where it was used to assess the expression of autophagy markers like LC3B.

Is the MAP LC3β antibody effective for detecting autophagy-related proteins in human cells?

The MAP LC3β antibody has been cited in research involving human cells, particularly in studies focusing on glioblastoma and systemic sclerosis, where it was used to analyze the expression of autophagy-related proteins, indicating its effectiveness in human cell applications.

What is the recommended dilution for using the MAP LC3β antibody in Western Blotting?

The MAP LC3β antibody is recommended to be used at a dilution of 1:1000 for Western Blotting, as indicated in various studies that employed this antibody for protein detection in their experimental setups.

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Mechanobiological and Molecular Alterations in the Aging Dentin-Pulp ComplexLife (Basel)May 20, 2026Neshka Manchorova-Veleva, Mina Pencheva, David Baruh, Veselina Todorova, Lyubomir Vangelov, Evgeni Ivanov, Margarita Guenova(F-2, sc-8019), JAK1 (A-9, sc-1677), COX2 (D-5, sc-514489), LAMP2 (H4B4, sc-188822), and MAP LC3β (G-2, sc-271625)—diluted 1:200 (Santa Cruz Biotechnology Inc., Dallas, TX, USA), using an automated Leica Bond-Max system

(2) Low Shear Stress Promotes Atherosclerosis by Mediating Pathological Accumulation of Endothelial Lipid Droplets via the KLF4/TFEB/ATP1A1 AxisJ Cardiovasc Dev DisMay 15, 2026Yi Shi, Ya-Nan Tan, Li-Da Wu, Li-Guo Wang, Yue Gu, Wen-Ying Zhou, Meng-Qian Shao, Jun-Xia Zhanganti-Phospho-TFEB (37681, Cell Signaling Technology), anti-ATP1A1 (14418-1-AP, Proteintech) and anti-LC3B (sc-271625, Santa Cruz Biotechnology). Western blot and fluorescent secondary antibodies were all purchased from

(3) Adenosine Receptor Functionality and Desensitization Machinery in a Neuronal Cell Model of Angelman SyndromeJ Dev BiolMay 2, 2026Martina Contestabile, Jacqueline Fátima Martins de Almeida, Chiara De Cesari, Ilaria Tonazzini, Paolo Giovanni Artini, Simona Danieleantibody binding. Primary antibodies included: MDM2 (sc-5304, Santa Cruz, Dallas, TX, USA; 1:200), LC3β (sc-271625, Santa Cruz; 1:500), phospho-p53 (sc-101762, Santa Cruz; 1:500), GRK2 (sc-562, Santa Cruz; 1:200), A1AR

(4) Alcohol exposure induces ferroptosis-dominated programmed cell death in esophageal epithelial cellsBMC Molecular and Cell BiologyApril 9, 2026Dongxue Wang, Zhenyu Jiang, Zhiyi Meng, Wei Hou, Tong Dang, Xianmei Meng, Jianyuan Chaiused in cell staining: PCNA (OriGene Technologies, Inc. #TA800894), LC3B (Santa Cruz Biotechnology, #sc-271625), endoG (Santa Cruz Biotechnology, #sc-365359), GSDMD (Cell Signaling Technology, #69469), BAX (Invitrogen,

(5) Anti-Cancer Effect of a New 5-FU Derivative Containing Triazole-Bearing Mannose (5-FUD-MAN) Against Human Breast Cancer Cells Through LC3B-Mediated Cell DeathJ Biochem Mol ToxicolMarch 29, 2026Ebru Şanci, Azada Aliyeva, Buket Bakan, Mustafa Özkaraca, Erkan Halay, Kadir Ay, Tamer Karayildirim, N. Ulku Karabay Yavasoglucleaved Caspase‐3 (Elabscience, Catalog No. E‐AB‐30004), LC3B (Santa Cruz Biotechnology, Catalog No. sc‐271625), AIF (Santa Cruz Biotechnology, Catalog No. Bs‐0037R), and ERK1/2 (Affinity Biosciences, Catalog No.

(6) Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing centerSci AdvMarch 27, 2026Jue Wang, Man Wu, Le Xiao, Gang Du, Muyuan Chen, Venkat G. Magupalli, Peter D. Dahlberg, Hao Wu, Grant J. JensenPrimary antibodies (ASC, 1:200; AdipoGen, AG25B0006C100; and LC3B, 1:20; Santa Cruz Biotechnology, sc-271625) were diluted in 1.5% BSA and incubated overnight with fixed cells at 4°C. After washing with 1× Dulbecco’s

(7) Lipid Overload Triggers PERK-ALCAT1-Mediated Mitophagy Failure in HepatocytesiScienceMarch 20, 2026Wenli Zhao, Yangguang Bao, Lei Liu, Yixin Gu, Xuran Liu, Óscar Monroig, Tingting Zhu, Peng Sun, Douglas R. Tocher, Qicun Zhou, et al.RRID: AB_2889972 anti-MFN2,"Abclonal, China",Cat#A19678; RRID: AB_2862729 anti-LC3B,Santa Cruz,Cat#SC-271625; RRID: AB_10714949 anti-PINK1,Santa Cruz,Cat#SC-518052; RRID: AB_2861352 anti-Parkin,"Wanlei bio,

(8) Prenatal lipopolysaccharide exposure programs cardiac fibrosis via dysregulating of connexin 43 in offspring ratsMolecular Medicine ReportsFebruary 24, 2026Yan Wen, Yao Yuan, Haigang Zhang, Ya Liuab11370), anti-microtubule-associated protein-1 light-chain (LC3; 1:1,000; Santa Cruz Biotechnology, Inc. sc-271625), anti-DNMT1 (1:500; Novus Biologicals, LLC; cat. no. NB100-56519), anti-DNMT3A (1:1,000; Novus Biologicals,

(9) Thrombospondin 1 aggravates cardiac remodeling in heart failure with preserved ejection fraction by inhibiting mitophagyiScienceFebruary 20, 2026Xingpeng Bu, Shuo Sha, Zhenzhen Zhang, Sicheng Bian, Shuhui Feng, Chunxia Li, Lei Wang, Huanzhen Chen3% BSA, and incubated overnight at 4°C with primary antibodies: Anti-LC3 (Santa Cruz Biotechnology, sc-271625, 1:300) and Anti-VDAC1 (Servicebio, GB111939, 1:300). The sections were then incubated with corresponding

(10) Inhibition of SDE2 Promotes Autophagy-Dependent Ferroptosis in Multiple MyelomaRedox BiologyJanuary 16, 2026Liang Xia, Jing Bao, Xiao-wen Chen, Yu-Chen Zhao, Xiang Wang, Yu Zhengwith antibodies against SDE2 (PA5-46779, Thermo Fisher), ATG5 (#2630, Cell Signaling Technology), LC3 (sc-271625, Santa Cruz), P62 (sc-28359, Santa Cruz), and GAPDH (ab8245, Abcam). 2.8 Co-immunoprecipitation (Co-IP) For

(11) Dysfunction of the Autophagy System and MDM2–p53 Axis Leads to the Accumulation of Amyloidogenic Proteins in Angelman Syndrome ModelsInternational Journal of Molecular SciencesNovember 14, 2025Jacqueline Fátima Martins de Almeida, Martina Contestabile, Ilaria Tonazzini, Chiara De Cesari, Laura Baroncelli, Claudia Martini, Simona Daniele1:500); p-62 (SQSTM1/p62, #5114, Cell Signaling Technology, Danvers, MA, USA, diluted 1:1000); LC3β (sc-271625, Santa Cruz Biotechnology, Santa Cruz, CA, USA, diluted 1:500); total p53 (sc-126, Santa Cruz Biotechnology,

(12) Inhibition of HCN Channels Enhances Oxidative Stress and Autophagy of NRK-52E Cells Under NH4Cl TreatmentInternational Journal of Molecular SciencesSeptember 21, 2025Zinaeli López-González, Laura I. Escobar, Daniel León-Aparicio, Abirán Fernando Mejía-Peralta, Teresa Padilla-Flores, Isabel Larre, Carolina Salvador, Omar Noel Medina-Campos, José Pedraza-Chaverri, Marisol de la Fuente-GranadaSanta Cruz Biotechnology, sc-48341, Dallas, TX, USA), anti-LC3B (1:250 dilution, Santa Cruz Biotechnology, sc-271625, Dallas, TX, USA), anti-p62 (1:500 dilution, Abnova, H00008878-M01, Neihu District, Taipei City, Taiwán),

(13) Induction of apoptosis and hypoxic stress in malignant melanoma cells via graphene-mediated far-infrared radiationBMC CancerApril 7, 2025Wumei Zhao, Ziwen Chen, Wenxing Fu, Chenyan Ye, Haijing Fu, Tianyi Xu, Binghui Wu, Lina Chen, Shi-Jun Shan(#42406), AIF (#5318), PARP (#9532), HIF-1α (#48085) from Cell Signaling Technology, USA; and MAP1LC3 (sc-271625) from Santa Cruz Biotechnology, CHN]. After thorough washing, secondary antibodies [Alexa Fluor® 488

(14) Advanced glycation end-products accelerate amyloid deposits in adipocyte's lipid dropletsCell death & diseaseNovember 19, 2024Izgilov R, Kislev N, Omari E, Benayahu D.serum albumin (BSA). The cells incubated with primary antibodies: LC3b (rabbit, Abcam ab192890; mouse, Sc-271625), GRP78 (rat; SC-13539), perilipin 1 (mouse; SC-390169), GLUT4 (mouse; SC-53566), ATGL (mouse; Santa Cruz

(15) Lactiplantibacillus plantarum 1008 Enhances Testicular Function and Spermatogenesis via the Modulation of Gut Microbiota in Male Mice with High-Fat-Diet-Induced ObesityBiology (Basel)October 31, 2024Chin-Yu Liu, Yi-Wen Chen, Tsung-Yu Tsai, Te-Hua Liu, Ting-Chia Chang, Chih-Wei TsaoAbcam), IL6 (1/500, sc-57315), Beclin 1 (1/1000, sc-48341), p62 (1/1000, sc-48402), LC3B-II (1/1000, sc-271625) (all from Santa Cruz Biotechnology), and β-actin (1/10,000, A5316; Sigma, St. Louis, MO, USA). 2.6.

(16) c-Jun N-terminal Kinase Supports Autophagy in Testicular Ischemia but Triggers Apoptosis in Ischemia-Reperfusion InjuryInternational Journal of Molecular SciencesSeptember 27, 2024Sarah R. Alotaibi, Waleed M. Renno, May Al-Maghrebinon-specific sites. Slides were then incubated overnight with MAP LC3b primary antibody (1:100 dilution; sc-271625; Santa Cruz Biotechnology, Dallas, TX, USA) at 4 °C in a moist, dark chamber. PBS-washed slides were

(17) Low PRKAB2 Expression Is Associated with Poor Outcomes in Pediatric Adrenocortical Tumors, and Treatment with Rottlerin Increases the PRKAB2 Level and Inhibits Tumorigenic Aspects in the NCI-H295R Adrenocortical Cancer Cell LineCancers (Basel)March 8, 2024Alcides Euzebio Tavares Xavier, Luciana Chain Veronez, Luís Fernando Peinado Nagano, Carolina Alves Pereira Correa, Mirela Baroni, Milena Silva Ramos, Rosane de Gomes de Paula Queiroz, Carlos Augusto Fernandes Molina, José Andres Yunes, Silvia Regina Brandalise, et al.Cell Signaling Technology (Danvers, MA, USA), and 1:2500 anti-GAPDH (sc-47724) and 1:500 MAP LC3B (sc-271625), obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Anti-mouse IgG 1:5000 (#7076) and anti-rabbit

(18) PACS-2 deficiency aggravates tubular injury in diabetic kidney disease by inhibiting ER-phagyCell Death & DiseaseOctober 4, 2023Jinfei Yang, Li Li, Chenrui Li, Wei Chen, Yan Liu, Shilu Luo, Chanyue Zhao, Yachun Han, Ming Yang, Hao Zhao, et al.methods Primary antibodies The following primary antibodies were used in this study: the anti-LC3B (sc-271625) was purchased from Santa Cruz Biotechnology; the anti-Collagen IV (ab6586), anti-Fibronectin (ab2413),

(19) MAT as a promising therapeutic strategy against triple-negative breast cancer via inhibiting PI3K/AKT pathwayScientific reportsJuly 31, 2023Wei S, Zhang Y, Ma X, Yao Y, Zhou Q, Zhang W, Zhou C, Zhuang J.and GAPDH (60004-1-Ig) were purchased from Proteintech (Wuhan, China) PGK1 (sc-130335) and LC3- II (sc-271625) were purchased from Santa Cruz Biotechnology, Inc., (Texas, United States), and BCL-2 (ab182858) and

(20) β-Carboline-α-aminophosphonate Derivative: A Promising Antitumor Agent for Breast Cancer TreatmentMolecules (Basel, Switzerland)May 8, 2023Zani CP, Zani AP, Thomazini CM, Retamiro KM, de Oliveira AR, Gonçalves DL, Sarragiotto MH, Garcia FP, de Oliveira Silva S, Nakamura CV, et al.(sc-56053), mouse anti-MMP-9 (sc-93859), mouse anti-cytochrome C (sc-13561), mouse anti-LC3I/LC3II (sc-271625), mouse anti-p62/SQSTM1 (sc-28359), and mouse anti-β-actin (sc-69879) were purchased from Santa Cruz Biotechnology

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MAP LC3β (G-2) Antibody

MAP LC3β (G-2) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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MAP LC3β (G-2) Antibody from Santa Cruz Biotechnology, Inc.

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