The Rabbit Anti-Cytokeratin 1/KRT1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Keratin 1, and KRT1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Cytokeratin 1/KRT1 Antibody has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
KRT1 (Keratin 1) is a Protein Coding gene. The protein encoded by this gene is a member of the keratin gene family. It belongs to the intermediate filament family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Mutations in the KRT1 gene underlie epidermolytic hyperkeratosis (EHK). This autosomal dominant disorder is characterized by phenotypic heterogeneity. Epidermolytic hyperkeratosis is a rare autosomal dominant inherited skin disorder caused by keratin 1 or keratin 10 mutations. Diseases associated with KRT1 include Palmoplantar Keratoderma, Nonepidermolytic and Ichthyosis Hystrix, Curth-Macklin Type