MyBioSource.com's Rabbit Anti-PFN1/Profilin 1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, and Western Blot. The Rabbit Anti-PFN1/Profilin 1 Antibody was generated using PFN1, and profilin 1 as the antigen and it reacts with Human.
Description
Mutations in the profilin 1 (PFN1) gene cause amyotrophic lateral sclerosis (ALS), a neurodegenerative disease caused by the loss of motor neurons leading to paralysis and eventually death. PFN1 is a small actin-binding protein that promotes formin-based actin polymerization and regulates numerous cellular functions