Rad50 Antibody (13B3)

Product Specs
ItemRad50 Antibody (13B3) - Azide and BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberNB100-147-0.1ml
Quantity0.1 ml
ApplicationsIF/IHC,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,In vitro assay,Knockdown Validated,Immunocytochemistry/ Immunofluorescence
FormatPBS
Conjugate/TagUnconjugated
ReactivityHuman,Monkey,Mouse,Rat
PurityProtein G purified
TargetRad50
Clone13B3
HostMouse
IsotypeIgG1
Molecular Weight153 kDa
Antibody TypePrimary Antibodies
ImmunogenAmino acids 1-425 of Rad50 expressed in E. coli
ClonalityMonoclonal
Research AreaBreast Cancer, DNA Repair, Homologous Recombination
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles
NCBI Full Gene NameRAD50 double strand break repair protein
NCBI Gene AliasesNBSLD, RAD502, hRad50

Specifications/Features

Available conjugates: Unconjugated

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuriaCell death & diseaseApril 1, 2021Nishad R, Mukhi D, Singh AK, Motrapu M, Chintala K, Tammineni P, Pasupulati AK.were purchased from Cell Signaling Technology (Danvers, MA). The anti-Ku80 (NBP156408), anti-RAD50 (NB100-147), anti-γ-H2AX (NB100-384), anti-Nephrin (NBP1-77303), anti-podocin (NBP2-75624), and anti-PCNA (NBP500-106).

(2) Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metforminBritish journal of cancerJanuary 1, 2020Sivalingam VN, Latif A, Kitson S, McVey R, Finegan KG, Marshall K, Lisanti MP, Sotgia F, Stratford IJ, Crosbie EJ.Supplementary Table 1. Primary antibodies used were HIF-1α (BD 610959, BD Biosciences, UK) and CA-9 (NB100-147, Novus Biological, Colorado, US). Translocase of the outer mitochondrial membrane 20 (TOMM20) (#sc-17764,

(3) Surface-Enhanced Raman Scattering Nanoparticles for Multiplexed Imaging of Bladder Cancer Tissue Permeability and Molecular PhenotypeACS nanoOctober 23, 2018Davis RM, Kiss B, Trivedi DR, Metzner TJ, Liao JC, Gambhir SS.staining, samples were fixed in PFA, stained with 0.2 μg/mL rabbit polyclonal anti-CA9 (Novus Biologicals NB100–147), and detected with anti-rabbit F(ab′)2-Alexa Fluor 647 conjugate (Cell signaling Technology, 4414S).

(4) Cancer initiating-cells are enriched in the CA9 positive fraction of primary cervix cancer xenograftsOncotargetJanuary 3, 2017Marie-Egyptienne DT, Chaudary N, Kalliomäki T, Hedley DW, Hill RP.Paraffin-embedded sections (4-μm thick) were dried in 60°C oven overnight. CA9 (Novus Biologicals, NB100-147, 1:2000) and Glut1 (Dako, A3536, 1:400) staining was carried out on a Ventana Benchmark XT fully automated

(5) HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacityNature communicationsMay 18, 2016Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, Miyazawa H, Yamaguchi Y, Miura M, Jenkins DM, et al.after matrigel implatation, skin tissues were removed and stained with carbonic anhydrase-IX (CA9; NB100-147, Novus Biological) and F4/80 (MCA497, AbD Serotec, Kidlington, UK). Macrophage recruitment was evaluated

(6) Listeria monocytogenes dampens the DNA damage responsePLoS pathogensOctober 1, 2014Samba-Louaka A, Pereira JM, Nahori MA, Villiers V, Deriano L, Hamon MA, Cossart P.following: NBS1 (Novus biologicals NB100-143), MDC1 (Novus biologicals NB100-395), RAD50 (Novus biologicals NB100-147). For Western blot analysis, cells were lysed with 2× Laemmli loading buffer (124 mM Tris-HCl [pH 6.8],

(7) FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistanceOncogeneAugust 7, 2014Khongkow P, Karunarathna U, Khongkow M, Gong C, Gomes AR, Yagüe E, Monteiro LJ, Kongsema M, Zona S, Man EP, et al.

(8) Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaksNucleic acids researchDecember 1, 2011Cheng Q, Barboule N, Frit P, Gomez D, Bombarde O, Couderc B, Ren GS, Salles B, Calsou P.

(9) Novel regulatory role for Kaposi's sarcoma-associated herpesvirus-encoded vFLIP in chemosensitization to bleomycinBiochemical and biophysical research communicationsNovember 18, 2011Masuda Y, Noguchi K, Segawa H, Tanaka N, Katayama K, Mitsuhashi J, Sugimoto Y.

(10) Ataxia telangiectasia mutated- and Rad3-related kinase drives both the early and the late DNA-damage response to the monofunctional antitumour alkylator S23906The Biochemical journalJuly 1, 2011Soares DG, Battistella A, Rocca CJ, Matuo R, Henriques JA, Larsen AK, Escargueil AE.

(11) Human T-lymphotropic type 1 virus p30 inhibits homologous recombination and favors unfaithful DNA repairBloodJune 2, 2011Baydoun HH, Pancewicz J, Nicot C.

(12) Two unrelated patients with MRE11A mutations and Nijmegen breakage syndrome-like severe microcephalyDNA repairMarch 7, 2011Matsumoto Y, Miyamoto T, Sakamoto H, Izumi H, Nakazawa Y, Ogi T, Tahara H, Oku S, Hiramoto A, Shiiki T, et al.

(13) SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtypeNature geneticsFebruary 1, 2011Stoepker C, Hain K, Schuster B, Hilhorst-Hofstee Y, Rooimans MA, Steltenpool J, Oostra AB, Eirich K, Korthof ET, Nieuwint AW, et al.

(14) The mTOR inhibitor rapamycin suppresses DNA double-strand break repairRadiation researchFebruary 1, 2011Chen H, Ma Z, Vanderwaal RP, Feng Z, Gonzalez-Suarez I, Wang S, Zhang J, Roti Roti JL, Gonzalo S, Zhang J.

(15) CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitorsCancer researchJanuary 15, 2011Anderson VE, Walton MI, Eve PD, Boxall KJ, Antoni L, Caldwell JJ, Aherne W, Pearl LH, Oliver AW, Collins I, et al.

(16) Bocavirus infection induces a DNA damage response that facilitates viral DNA replication and mediates cell deathJournal of virologyJanuary 1, 2011Luo Y, Chen AY, Qiu J.

(17) Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiationNucleic acids researchDecember 1, 2010Gomez-Godinez V, Wu T, Sherman AJ, Lee CS, Liaw LH, Zhongsheng Y, Yokomori K, Berns MW.

(18) Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytesJournal of immunology (Baltimore, Md. : 1950)December 1, 2010Machida K, McNamara G, Cheng KT, Huang J, Wang CH, Comai L, Ou JH, Lai MM.

(19) Physical interaction between the herpes simplex virus type 1 exonuclease, UL12, and the DNA double-strand break-sensing MRN complexJournal of virologyDecember 1, 2010Balasubramanian N, Bai P, Buchek G, Korza G, Weller SK.

(20) Telomerase-dependent oncolytic adenovirus sensitizes human cancer cells to ionizing radiation via inhibition of DNA repair machineryCancer researchNovember 15, 2010Kuroda S, Fujiwara T, Shirakawa Y, Yamasaki Y, Yano S, Uno F, Tazawa H, Hashimoto Y, Watanabe Y, Noma K, et al.

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