EPCR Antibody AF2749 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemEPCR Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $539.00Supplier Page View Company Product Page
Catalog NumberAF2749
NCBI Gene AliasesEPCR, Epcr, Ccca, CCCA, Ccd41, CCD41
ApplicationsFlow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready
HostGoat
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)
ReactivityMouse,Transgenic Mouse
IsotypeIgG
TargetEPCR
NCBI Full Gene Nameprotein C receptor, endothelial, protein C receptor
ClonalityPolyclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse EPCR, Ala17-Ser214, Accession # Q64695
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse EPCR in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant human EPCR is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Vascularization of neonatal liver lobules presages adult liver sizeNature CommunicationsNovember 13, 2025D. Berfin Azizoglu, Karina Perez, Sherry Li Zheng, Shahadat Rahman, Ellen Youngsoo Rim, Teni Anbarchian, Matt Fish, Kyle M. Loh, Kristy Red-Horse, Roel Nussecompresstome sections, iDisco whole lobe samples, or paraffin sections: goat anti-EPCR (R&D Systems, AF2749, 1:100), rat anti-Endomucin (Santa Cruz Biotech, sc-65495, 1:100), rabbit anti-phospho histone H3 (Milipore

(2) Endothelial Protein C Receptor and 3K3A-Activated Protein C Protect Mice from Allergic Contact Dermatitis in a Contact Hypersensitivity ModelInternational journal of molecular sciencesJanuary 19, 2024Xue M, Jackson CJ, Lin H, Zhao R, Liang HPH, Weiler H, Griffin JH, March L.

(3) The endothelial protein C receptor plays an essential role in the maintenance of pregnancyScience advancesNovember 1, 2020Castillo MM, Yang Q, Sigala AS, McKinney DT, Zhan M, Chen KL, Jarzembowski JA, Sood R.EPCR immunostaining was done with anti-EPCR primary antibodies at a dilution of 1:200 (catalog no. AF2749, R&D systems, Minneapolis, MN) and biotinylated rabbit anti-goat secondary antibodies at a dilution

(4) Multicolor quantitative confocal imaging cytometryNature methodsJanuary 1, 2018Coutu DL, Kokkaliaris KD, Kunz L, Schroeder T.

(5) Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactorPloS oneJanuary 1, 2013Greineder CF, Chacko AM, Zaytsev S, Zern BJ, Carnemolla R, Hood ED, Han J, Ding BS, Esmon CT, Muzykantov VR.BioLegend (San Diego, CA). Anti-TM polyclonal antibody (AF3894) and anti-EPCR polyclonal antibody (AF2749) were purchased from R&D systems (Minneapolis, MN). Anti-EPCR blocking antibody, mAb1560, was supplied

(6) N-cadherin+ HSCs in fetal liver exhibit higher long-term bone marrow reconstitution activity than N-cadherin- HSCsBiochemical and biophysical research communicationsNovember 23, 2012Toyama H, Arai F, Hosokawa K, Ikushima YM, Suda T.

(7) Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) miceThe Journal of biological chemistryMay 11, 2012Xue M, Dervish S, Harrison LC, Fulcher G, Jackson CJ.

(8) The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptorsThe Journal of biological chemistryFebruary 18, 2011Disse J, Petersen HH, Larsen KS, Persson E, Esmon N, Esmon CT, Teyton L, Petersen LC, Ruf W.

(9) Activated protein C protects against ventilator-induced pulmonary capillary leakAmerican journal of physiology. Lung cellular and molecular physiologyJune 1, 2009Finigan JH, Boueiz A, Wilkinson E, Damico R, Skirball J, Pae HH, Damarla M, Hasan E, Pearse DB, Reddy SP, et al.

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EPCR Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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EPCR Antibody from R&D Systems, a Bio-Techne Brand

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